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NCT03234361 · ClinicalTrials.gov registry record · Phase 2
Preventing Hypertension and Sympathetic Overactivation by Targeting Phosphate
A Phase 2 study, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- Phase 2
- Development phase
- 94
- Enrollment target
NCT03234361 is a Phase 2 study that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 94 participants.
The verdict
NCT03234361, a Phase 2 study, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 94 participants
- Enrollment target
Study Summary
An increasing number of studies have indicated that most fast food and common grocery items, contain large amount of inorganic phosphate-based food additives , which are highly absorbable. The long-term cardiovascular consequences of a high phosphate diet are unknown but the existing database implicates phosphate excess as an independent risk factor for cardiovascular events in individuals with and without chronic kidney diseases (CKD). High phosphate consumption clearly induces BP elevation in rats with normal kidneys. However, the mechanisms underlying phosphate-induced hypertension and the relevance of these rodent studies to human hypertension have not been determined. We seek to investigate the role of high phosphate diet in human hypertension and assess the effect of high phosphate diet on muscle sympathetic nerve activity and the exercise pressor reflex.
Interventions
- DIETARY_SUPPLEMENT High Phosphate Phase
- DIETARY_SUPPLEMENT Low Phosphate Phase
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 94 participants |
| Start Date | 2017-10-16 |
| Est. Completion | 2022-09-30 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03234361
The ClinicalTrials.gov registry entry for NCT03234361 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 94 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which High Phosphate Phase is the first listed.
NCT03234361 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03234361 about?
NCT03234361 is a clinical study titled "Preventing Hypertension and Sympathetic Overactivation by Targeting Phosphate". An increasing number of studies have indicated that most fast food and common grocery items, contain large amount of inorganic phosphate-based food additives , which are highly absorbable. The long-term cardiovascular consequences of a high phosphate diet are unknown but the existing database implic...
What is the current status of trial NCT03234361?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 94 participants. The study started on 2017-10-16. Estimated completion is 2022-09-30.
What interventions are being tested in trial NCT03234361?
The interventions under investigation include: High Phosphate Phase (DIETARY_SUPPLEMENT), Low Phosphate Phase (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT03234361?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
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