Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03233594 · ClinicalTrials.gov registry record
PET Imaging of Chronic Pain Syndromes
A clinical trial of Chronic Pain Syndrome, sponsored by Thomas Jefferson University.
- Active
- Registry status
- 32
- Enrollment target
- 2
- Study locations
NCT03233594: Active study of Chronic Pain Syndrome, sponsored by Thomas Jefferson University.
NCT03233594 is a study of Chronic Pain Syndrome that is active but no longer recruiting, run by Thomas Jefferson University. The registered enrollment target is 32 participants, below the 96-participant average among 7 other Chronic Pain Syndrome trials with a reported enrollment target (67% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03233594, a study of Chronic Pain Syndrome, is active but no longer recruiting, sponsored by Thomas Jefferson University.
- ACTIVE NOT RECRUITING
- Registry status
- 32 participants
- Enrollment target
- 2
- Study locations
Study Summary
Central nervous system (CNS) changes associated with pain have been difficult to measure until the development of functional neuroimaging techniques such as positron emission tomography (PET). We have previously observed asymmetry in the thalamus associated with chronic pain that altered during acupuncture therapy. Imaging studies of therapeutic techniques for chronic pain in animals and humans have been quite limited. This study will be the first to utilize FDG PET-MRI imaging of both the brain and body in order to assess CNS changes and peripheral body changes related to chronic pain and its potential management.
Primary Outcome
To use PET-MRI to define abnormal brain and body activity and evaluate changes in inflammation in painful regions in patients with chronic pain syndromes.
Conditions Studied
Interventions
- OTHER Chiropractic Group
- OTHER Healthy Control Group
Study Locations (2)
Pennsylvania
- Thomas Jefferson University, Marcus Institute of Integrative Health Centers - Philadelphia
- Thomas Jefferson University, Marcus Institute of Integrative Health Centers - Villanova
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2017-06-07 |
| Est. Completion | 2026-04-01 |
What the registry record for NCT03233594 still lists
NCT03233594 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 96-participant average among 7 other Chronic Pain Syndrome trials with a reported enrollment target (67% lower).
The record links to 1 condition, with Chronic Pain Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Chiropractic Group is the first listed.
NCT03233594 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT03233594 about?
NCT03233594 is a clinical study titled "PET Imaging of Chronic Pain Syndromes". Central nervous system (CNS) changes associated with pain have been difficult to measure until the development of functional neuroimaging techniques such as positron emission tomography (PET). We have previously observed asymmetry in the thalamus associated with chronic pain that altered during acup...
What is the current status of trial NCT03233594?
This trial is currently active not recruiting. The enrollment target is 32 participants. The study started on 2017-06-07. Estimated completion is 2026-04-01.
What conditions does trial NCT03233594 study?
This clinical trial studies the following conditions: Chronic Pain Syndrome.
What interventions are being tested in trial NCT03233594?
The interventions under investigation include: Chiropractic Group (OTHER), Healthy Control Group (OTHER).
Who is sponsoring clinical trial NCT03233594?
This trial is sponsored by Thomas Jefferson University, which has 292 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03233594 being conducted?
This trial has 2 study locations across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Pain Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Mind Body Syndrome Therapy for Chronic Pain
RECRUITING · NA
-
Mind Body Intervention for Chronic Upper Extremity Pain (Repetitive Stress Injury)
RECRUITING · NA
-
Interoceptive Awareness and Function in Adolescents With Chronic Pain
RECRUITING
-
SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease
RECRUITING · NA
-
STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis
RECRUITING · Phase 1
-
Predictors of Pain Relief From Mindfulness-based Stress Reduction (MBSR) in Multiple Forms of Chronic Pain Patients
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02445781 · 32 participants · Early Phase 1
Differing Levels of Hypoglycemia
- NCT02792270 · 32 participants · NA
Caloric Restriction In Sarcoma Patients Treated With Pre-Operative RT
- NCT03068910 · 32 participants · Early Phase 1
Hyperandrogenemia and Altered Day-night LH Pulse Patterns
- NCT03208868 · 32 participants · NA
Leucine Enriched Essential Amino Acid Mixture to Reverse Muscle Loss in Cirrhosis
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI