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NCT03233191 · ClinicalTrials.gov registry record · Phase 3
Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer
A Phase 3 study of Breast Screening, sponsored by ECOG-ACRIN Cancer Research Group.
- Active
- Registry status
- Phase 3
- Development phase
- 108,508
- Enrollment target
- 20
- Study locations
NCT03233191: Active Phase 3 study of Breast Screening, sponsored by ECOG-ACRIN Cancer Research Group.
NCT03233191 is a Phase 3 study of Breast Screening that is active but no longer recruiting, run by ECOG-ACRIN Cancer Research Group. The registered enrollment target is 108,508 participants, above the 765-participant average among 15,282 other Phase 3 trials with a reported enrollment target (14084% higher). The trial reports 20 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03233191, a Phase 3 study of Breast Screening, is active but no longer recruiting, sponsored by ECOG-ACRIN Cancer Research Group.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 108,508 participants
- Enrollment target
- 20
- Study locations
Study Summary
This randomized phase III trial studies digital tomosynthesis mammography and digital mammography in screening patients for breast cancer. Screening for breast cancer with tomosynthesis mammography may be superior to digital mammography for breast cancer screening and may help reduce the need for additional imaging or treatment.
Primary Outcome
The cumulative proportions of participants experiencing the primary endpoint in the two study arms will be compared. The primary comparison of the two study arms will be approached from an Intent-to-Treat perspective and will be based on a two-sided test for comparing binomial proportions.
Conditions Studied
Interventions
- OTHER Laboratory Biomarker Analysis
- PROCEDURE Digital Tomosynthesis Mammography
- PROCEDURE Digital Mammography
Study Locations (20)
Colorado
- UCHealth University of Colorado Hospital - Aurora
- Penrose-Saint Francis Healthcare - Colorado Springs
- The Women's Imaging Center - Denver
- Radiology Imaging Associates - Englewood
- UCHealth Highlands Ranch Hospital - Highlands Ranch
- UCHealth Lone Tree Health Center - Lone Tree
Arizona
- Banner-University Medical Center Phoenix - Phoenix
- University of Arizona College of Medicine Phoenix - Phoenix
- Valleywise Comprehensive Health Center - Phoenix - Phoenix
- Mayo Clinic Hospital in Arizona - Phoenix
- Scottsdale Medical Imaging Limited - Scottsdale
California
- Kern Radiology Medical Group Inc - Bakersfield
- Los Angeles General Medical Center - Los Angeles
- USC / Norris Comprehensive Cancer Center - Los Angeles
- Kaiser Permanente-Modesto - Modesto
- Zuckerberg San Francisco General Hospital - San Francisco
Alabama
- University of Alabama at Birmingham Cancer Center - Birmingham
- Mobile Infirmary Medical Center - Mobile
Arkansas
- University of Arkansas for Medical Sciences - Little Rock
Delaware
- Helen F Graham Cancer Center - Newark
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 108,508 participants |
| Start Date | 2017-09-28 |
| Est. Completion | 2030-12-31 |
| Phase | Phase 3 |
What the registry record for NCT03233191 still lists
NCT03233191 is an interventional study that assigns participants to a tested intervention. Its 108,508 participants enrollment target places it among the larger protocols in the corpus, above the 765-participant average among 15,282 other Phase 3 trials with a reported enrollment target (14084% higher).
The record links to 1 condition, with Breast Screening appearing as the primary indexed condition, and to 3 interventions - of which Laboratory Biomarker Analysis is the first listed.
NCT03233191 names 20 study sites across 6 states, led by Colorado, Arizona, California.
Frequently Asked Questions
What is clinical trial NCT03233191 about?
NCT03233191 is a clinical study titled "Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer". This randomized phase III trial studies digital tomosynthesis mammography and digital mammography in screening patients for breast cancer. Screening for breast cancer with tomosynthesis mammography may be superior to digital mammography for breast cancer screening and may help reduce the need for ad...
What is the current status of trial NCT03233191?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 108,508 participants. The study started on 2017-09-28. Estimated completion is 2030-12-31.
What conditions does trial NCT03233191 study?
This clinical trial studies the following conditions: Breast Screening.
What interventions are being tested in trial NCT03233191?
The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Digital Tomosynthesis Mammography (PROCEDURE), Digital Mammography (PROCEDURE).
Who is sponsoring clinical trial NCT03233191?
This trial is sponsored by ECOG-ACRIN Cancer Research Group, which has 75 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03233191 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Screening
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03233191's enrollment target sits among peer trials
108,508 1st of 2000 higher than 2,000 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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