Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03228641 · ClinicalTrials.gov registry record · NA
Evaluation of Safety and Efficacy of Micro-coring Device for Treatment of Facial Wrinkles and Skin Laxity
A NA study of Wrinkle and Facial and Neck Skin Laxity, sponsored by Cytrellis Biosystems.
- Completed
- Registry status
- NA
- Development phase
- 33
- Enrollment target
- 5
- Study locations
NCT03228641: Completed NA study of Wrinkle and Facial and Neck Skin Laxity, sponsored by Cytrellis Biosystems.
NCT03228641 is a NA study of Wrinkle and Facial and Neck Skin Laxity that has completed, run by Cytrellis Biosystems. The registered enrollment target is 33 participants, below the 119-participant average among 25 other Wrinkle trials with a reported enrollment target (72% lower). The trial reports 5 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03228641, a NA study of Wrinkle and Facial and Neck Skin Laxity, has completed, sponsored by Cytrellis Biosystems.
- COMPLETED
- Registry status
- NA
- Development phase
- 33 participants
- Enrollment target
- 5
- Study locations
Study Summary
A pilot study is designed to evaluate safety and efficacy of the Micro-Coring (MC) technology for treatment of facial wrinkles. MC device employs hollow coring needles that enable safe, rapid, and effective full-thickness small skin cores (200-500 microns in diameter) removal initiating a skin repair process through formation of new collagen and elastin fibers (skin rejuvenation).
Primary Outcome
One grade or better improvement in score on Wrinkle Severity Scale
Conditions Studied
Interventions
- DEVICE micro-excisional skin removal with coring needle
Study Locations (5)
California
- Laser & Skin Center of Northern CA - Sacramento
Massachusetts
- SkinCare Physicians - Chestnut Hill
New York
- Laser & Skin Surgery Center of NY - New York
Tennessee
- Nashville Center for Laser & Facial Surgery - Nashville
Texas
- Dr A Jay Burns Cosmetic Surgery - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2016-06-01 |
| Est. Completion | 2018-04-30 |
| Phase | NA |
What the finished NCT03228641 record still lists
NCT03228641 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 33 participants, a relatively small participant target, below the 119-participant average among 25 other Wrinkle trials with a reported enrollment target (72% lower).
The record links to 2 conditions, with Wrinkle appearing as the primary indexed condition, and to 1 intervention - of which micro-excisional skin removal with coring needle is the first listed.
NCT03228641 lists 5 locations in 5 states (California, Massachusetts, New York).
Frequently Asked Questions
What is clinical trial NCT03228641 about?
NCT03228641 is a clinical study titled "Evaluation of Safety and Efficacy of Micro-coring Device for Treatment of Facial Wrinkles and Skin Laxity". A pilot study is designed to evaluate safety and efficacy of the Micro-Coring (MC) technology for treatment of facial wrinkles. MC device employs hollow coring needles that enable safe, rapid, and effective full-thickness small skin cores (200-500 microns in diameter) removal initiating a skin repai...
What is the current status of trial NCT03228641?
This trial is currently completed. It is a NA study. The enrollment target is 33 participants. The study started on 2016-06-01. Estimated completion is 2018-04-30.
What conditions does trial NCT03228641 study?
This clinical trial studies the following conditions: Wrinkle, Facial and Neck Skin Laxity.
What interventions are being tested in trial NCT03228641?
The interventions under investigation include: micro-excisional skin removal with coring needle (DEVICE).
Who is sponsoring clinical trial NCT03228641?
This trial is sponsored by Cytrellis Biosystems, which has 8 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03228641 being conducted?
This trial has 5 study locations across California, Massachusetts, New York, Tennessee, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Wrinkle
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03228641's enrollment target sits among peer trials
33 17th of 25 higher than 9 of 25 other Wrinkle trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Wrinkle trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles
RECRUITING · NA
-
AVAVA MIRIA General Use
RECRUITING · NA
-
Feasibility Study to Collect and Assess Safety Data for a Radiofrequency Microneedling Device for Electrocoagulation and Hemostasis of Soft Tissues for Dermatologic Conditions
RECRUITING · NA
-
The Effects of Almond on Facial Skin Collagen and Wrinkles
RECRUITING · NA
-
A Prospective Controlled Study to Evaluate the Safety and Effectiveness of Thermage® FLX Radiofrequency Treatment
RECRUITING · NA
-
Clinical Study to Evaluate the Safety and Efficacy of Candela Technology
ACTIVE NOT RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02861898 · 33 participants · Phase 1
Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma
- NCT04871607 · 33 participants · Phase 2
Yttrium-90 Labeled Anti-CD25 Monoclonal Antibody Combined With BEAM Chemotherapy Conditioning for the Treatment of Primary Refractory or Relapsed Hodgkin Lymphoma
- NCT05071937 · 33 participants · Phase 2
ZEN003694 Combined With Talazoparib in Patients With Recurrent Ovarian Cancer
- NCT05168618 · 33 participants · Phase 2
Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer, The AtezoCab Trial
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI