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NCT03223636 · ClinicalTrials.gov registry record
Measuring the Latency Connectome in the Central Nervous Systems Using Neuroimaging and Neurophysiological Techniques
A clinical trial, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 16
- Enrollment target
NCT03223636: Completed study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT03223636 is a clinical trial that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 16 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03223636 has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 16 participants
- Enrollment target
Study Summary
Background: Little is known about the time it takes for nerve signals to go from one area of the brain to another. Using advanced methods for brain research, researchers want to look at the time it takes to send messages between different brain areas. They also want to develop new tests. Objectives: To develop tests to measure the sizes of nerve fibers in the peripheral nerve system and in the brain. Also to find out the different speeds that information travels in nerve fibers. Eligibility: Healthy, right-handed people ages 18-70 Design: Participants will be screened with medical history and a physical exam. Participants will have up to 7 visits depending on the tests they choose. Visits last about 2-4 hours and may involve the following tests: * Physical exam * Urine tests * Magnetic resonance imaging (MRI). Participants lie on a table that slides into a scanner. They will be in the scanner for up to 1 hour. For some scans, sensors are placed on the skin. They will get earplugs for loud noises. * Small, sticky pads on the skin will electrically stimulate nerves in the forearm. * Transcranial magnetic stimulation (TMS). A wire coil will be held to the scalp. A brief electrical current passes through the coil to affect brain activity. * Electroencephalography. TMS will be given to the brain. Small electrodes on the scalp measure brain activity. Participants may do small tasks. * Electrodes on the scalp will send an electrical current to the brain. * A cone with magnetic detectors will be lowered onto the head to record brain activity. Participants will perform various tasks.
Primary Outcome
For TMS, we will measure motor evoked potential (MEP) amplitude
Interventions
- DEVICE TMS
- DEVICE MRI
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2017-10-02 |
| Est. Completion | 2021-02-26 |
What the finished NCT03223636 record still lists
NCT03223636 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 16 participants, a relatively small participant target.
The record links to 0 conditions, and to 2 interventions - of which TMS is the first listed.
NCT03223636 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03223636 about?
NCT03223636 is a clinical study titled "Measuring the Latency Connectome in the Central Nervous Systems Using Neuroimaging and Neurophysiological Techniques". Background: Little is known about the time it takes for nerve signals to go from one area of the brain to another. Using advanced methods for brain research, researchers want to look at the time it takes to send messages between different brain areas. They also want to develop new tests. Objective...
What is the current status of trial NCT03223636?
This trial is currently completed. The enrollment target is 16 participants. The study started on 2017-10-02. Estimated completion is 2021-02-26.
What interventions are being tested in trial NCT03223636?
The interventions under investigation include: TMS (DEVICE), MRI (DEVICE).
Who is sponsoring clinical trial NCT03223636?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
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