Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03219411 · ClinicalTrials.gov registry record · Phase 2

Effects of Cinnamon Supplementation on Glucose Metabolism in Patients With Pre-diabetes

A Phase 2 study, sponsored by Joslin Diabetes Center.

Completed
Registry status
Phase 2
Development phase
12
Enrollment target

NCT03219411: Completed Phase 2 study, sponsored by Joslin Diabetes Center.

NCT03219411 is a Phase 2 study that has completed, run by Joslin Diabetes Center. The registered enrollment target is 12 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03219411, a Phase 2 study, has completed, sponsored by Joslin Diabetes Center.

COMPLETED
Registry status
Phase 2
Development phase
12 participants
Enrollment target

Study Summary

The transition from normal glucose tolerance to overt type 2 diabetes mellitus (T2D) encompasses a variety of glycemic abnormalities that are commonly referred to as 'prediabetes'. While intensive lifestyle interventions are the cornerstone of T2D prevention, developing safe, cost-effective adjunct therapeutic strategies is a clinically relevant goal. Cinnamon supplementation has been shown to improve fasting plasma glucose in patients with T2D. This placebo-controlled, randomized study will determine if cinnamon improves glucose homeostasis in patients with prediabetes over a 12-week period.

Primary Outcome

Change from baseline in fasting plasma glucose at 12 weeks

Interventions

  • OTHER placebo
  • DIETARY_SUPPLEMENT Cinnamon

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2017-08-28
Est. Completion 2019-07-30
Phase Phase 2
Joslin Diabetes Center

73 total trials

What the finished NCT03219411 record still lists

NCT03219411 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower).

The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.

NCT03219411 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03219411 about?

NCT03219411 is a clinical study titled "Effects of Cinnamon Supplementation on Glucose Metabolism in Patients With Pre-diabetes". The transition from normal glucose tolerance to overt type 2 diabetes mellitus (T2D) encompasses a variety of glycemic abnormalities that are commonly referred to as 'prediabetes'. While intensive lifestyle interventions are the cornerstone of T2D prevention, developing safe, cost-effective adjunct ...

What is the current status of trial NCT03219411?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2017-08-28. Estimated completion is 2019-07-30.

What interventions are being tested in trial NCT03219411?

The interventions under investigation include: placebo (OTHER), Cinnamon (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT03219411?

This trial is sponsored by Joslin Diabetes Center, which has 73 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03219411's enrollment target sits among peer trials

12 1948th of 2000 higher than 34 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02602769 · 12 participants

    Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome

  • NCT02605421 · 12 participants · Phase 2

    Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma

  • NCT02619448 · 12 participants · Early Phase 1

    Concurrent Chemotherapy Plus HFR Radiation Therapy in Inoperable NSCLC

  • NCT03311503 · 12 participants · Phase 1

    Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03219411, the US trial registry maintained by the National Library of Medicine. NCT03219411 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.