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ACTIVE NOT RECRUITING Phase 3

NOVOCART 3D Treatment Following Microfracture Failure

NCT03219307 · View on ClinicalTrials.gov ↗

Study Summary

This study is prospective single arm extension study of protocol AAG-G-H-1220. It is open only to participants of AAG-G-H-1220 randomized to the Microfracture treatment group.

Conditions Studied

Interventions

  • COMBINATION_PRODUCT NOVOCART 3D

Study Locations (5)

Illinois

  • Rush University Medical Center — Chicago

Ohio

  • Ohio State University Wexner Medical Center — Columbus

Utah

  • Alpine Orthopaedics — North Logan

Alberta

  • University of Alberta — Edmonton

Nova Scotia

  • Dalhousie University — Halifax

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2018-11-30
Est. Completion 2029-01
Phase Phase 3

Sponsor

Aesculap Biologics

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03219307

The ClinicalTrials.gov registry entry for NCT03219307 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Aesculap Biologics, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Articular Cartilage Defect appearing as the primary indexed condition, and to 1 intervention — of which NOVOCART 3D is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03219307 reports 5 study locations spanning 5 distinct geographic areas — top geographies include Illinois, Ohio, Utah. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03219307 about?

NCT03219307 is a clinical study titled "NOVOCART 3D Treatment Following Microfracture Failure". This study is prospective single arm extension study of protocol AAG-G-H-1220. It is open only to participants of AAG-G-H-1220 randomized to the Microfracture treatment group.

What is the current status of trial NCT03219307?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 30 participants. The study started on 2018-11-30. Estimated completion is 2029-01.

What conditions does trial NCT03219307 study?

This clinical trial studies the following conditions: Articular Cartilage Defect. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03219307?

The interventions under investigation include: NOVOCART 3D (COMBINATION_PRODUCT). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03219307?

This trial is sponsored by Aesculap Biologics, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03219307 being conducted?

This trial has 5 study locations across Illinois, Ohio, Utah, Alberta, Nova Scotia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial