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NCT03218085 · ClinicalTrials.gov registry record
Role of Exogenous and Endogenous Sex Hormones on Tenofovir and Emtricitabine Disposition in Female Genital Tract
A clinical trial, sponsored by University of Minnesota.
- Completed
- Registry status
- 28
- Enrollment target
NCT03218085 is a clinical trial that has completed, run by University of Minnesota. The registered enrollment target is 28 participants.
The verdict
NCT03218085 has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- 28 participants
- Enrollment target
Study Summary
Cervical biopsies will be collected from women aged 18 and over whom are virally suppressed and taking tenofovir as part of their antiretroviral therapy regimen. Blood plasma, peripheral blood mononuclear cells (PBMC), and cervicovaginal swabs will also be collected. Drug concentrations, hormone concentrations, inflammatory cytokines, and vaginal microbiome will be evaluated to understand the role of hormones, inflammation, and the microbiome in modulating drug efficacy in the female genital tract.
Interventions
- DRUG Tenofovir
- DRUG Emtricitabine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2017-07-14 |
| Est. Completion | 2024-02-15 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03218085
The ClinicalTrials.gov registry entry for NCT03218085 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Minnesota, which has 966 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Tenofovir is the first listed.
NCT03218085 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03218085 about?
NCT03218085 is a clinical study titled "Role of Exogenous and Endogenous Sex Hormones on Tenofovir and Emtricitabine Disposition in Female Genital Tract". Cervical biopsies will be collected from women aged 18 and over whom are virally suppressed and taking tenofovir as part of their antiretroviral therapy regimen. Blood plasma, peripheral blood mononuclear cells (PBMC), and cervicovaginal swabs will also be collected. Drug concentrations, hormone con...
What is the current status of trial NCT03218085?
This trial is currently completed. The enrollment target is 28 participants. The study started on 2017-07-14. Estimated completion is 2024-02-15.
What interventions are being tested in trial NCT03218085?
The interventions under investigation include: Tenofovir (DRUG), Emtricitabine (DRUG).
Who is sponsoring clinical trial NCT03218085?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
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