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COMPLETED

Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma Survivors

NCT03206450 · View on ClinicalTrials.gov ↗

Study Summary

This research trial studies saliva, semen, and blood samples to determine effects of chemotherapy on fertility in osteosarcoma survivors. Study biospecimen samples from osteosarcoma survivors in the laboratory may help doctors learn whether chemotherapy causes fertility problems and to learn more about the long term effects.

Conditions Studied

Interventions

  • PROCEDURE Biospecimen Collection
  • OTHER Laboratory Biomarker Analysis
  • OTHER Questionnaire Administration

Study Locations (20)

California

  • Kaiser Permanente Downey Medical Center — Downey
  • City of Hope Comprehensive Cancer Center — Duarte
  • Children's Hospital Los Angeles — Los Angeles
  • UCSF Benioff Children's Hospital Oakland — Oakland
  • Kaiser Permanente-Oakland — Oakland
  • Lucile Packard Children's Hospital Stanford University — Palo Alto
  • University of California Davis Comprehensive Cancer Center — Sacramento
  • Rady Children's Hospital - San Diego — San Diego
  • Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center — Torrance

Florida

  • Broward Health Medical Center — Fort Lauderdale
  • Golisano Children's Hospital of Southwest Florida — Fort Myers
  • University of Florida Health Science Center - Gainesville — Gainesville

Arizona

  • Phoenix Childrens Hospital — Phoenix
  • Banner University Medical Center - Tucson — Tucson

Connecticut

  • Connecticut Children's Medical Center — Hartford
  • Yale University — New Haven

Alabama

  • Children's Hospital of Alabama — Birmingham

Colorado

  • Children's Hospital Colorado — Aurora

Delaware

  • Alfred I duPont Hospital for Children — Wilmington

District of Columbia

  • MedStar Georgetown University Hospital — Washington D.C.

Trial Details

FieldValue
Enrollment Target 224 participants
Start Date 2017-12-06
Est. Completion 2024-06-30

Sponsor

Children's Oncology Group

318 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03206450

The ClinicalTrials.gov registry entry for NCT03206450 describes a study currently listed as completed. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 224 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Children's Oncology Group, which has 318 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Osteosarcoma appearing as the primary indexed condition, and to 3 interventions — of which Biospecimen Collection is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03206450 reports 20 study locations spanning 8 distinct geographic areas — top geographies include California, Florida, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03206450 about?

NCT03206450 is a clinical study titled "Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma Survivors". This research trial studies saliva, semen, and blood samples to determine effects of chemotherapy on fertility in osteosarcoma survivors. Study biospecimen samples from osteosarcoma survivors in the laboratory may help doctors learn whether chemotherapy causes fertility problems and to learn more ab...

What is the current status of trial NCT03206450?

This trial is currently completed. The enrollment target is 224 participants. The study started on 2017-12-06. Estimated completion is 2024-06-30.

What conditions does trial NCT03206450 study?

This clinical trial studies the following conditions: Osteosarcoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03206450?

The interventions under investigation include: Biospecimen Collection (PROCEDURE), Laboratory Biomarker Analysis (OTHER), Questionnaire Administration (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03206450?

This trial is sponsored by Children's Oncology Group, which has 318 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03206450 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial