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NCT03206112 · ClinicalTrials.gov registry record
Loss of Depotentiation in Focal Dystonia
A clinical trial, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Terminated
- Registry status
- 6
- Enrollment target
NCT03206112: Clinical Trial study, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT03206112 is a clinical trial that was terminated before completion, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 6 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03206112 was terminated before completion, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- TERMINATED
- Registry status
- 6 participants
- Enrollment target
Study Summary
Background Focal dystonia is a brain disorder. It affects a muscle or muscles in a specific part of the body. Researchers think it may be related to excessive training or practice. They want to know more about how much training might trigger focal dystonia. Objectives: To study why people develop focal dystonia. To study how brain plasticity changes with focal dystonia. Eligibility: People at least 18 years of age with focal dystonia. Healthy volunteers the same age are also needed. Design: Participants will be screened with a physical exam and questions. They may have blood and urine tests. Participants will have up to 3 testing visits. Participants will have small electrodes stuck on the skin on the hands or arms. Muscle activity will be recorded. Participants will have transcranial magnetic stimulation (TMS). A wire coil will be placed onto the scalp. A brief electrical current will pass through the coil. The current will create a magnetic field that affects brain activity. Participants may be asked to tense certain muscles or do simple actions during TMS. A nerve at the wrist will get weak electrical stimulation. The stimulation may be paired with TMS for very short times. Participants will receive repeated magnetic pulses. Participants will receive a total of 150 pulses during a 10-second period. An entire testing visit will last about 3 hours. ...
Primary Outcome
compare MEP amplitude in patients with that in healthy volunteers to identify whether depotentiation is weaker in focal dystonia
Interventions
- OTHER PAS25
- OTHER PAS10
- OTHER PAS25-cTBS150
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2017-09-20 |
| Est. Completion | 2020-04-09 |
Why NCT03206112 stopped before completion
NCT03206112 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 6 participants, a relatively small participant target.
The record links to 0 conditions, and to 3 interventions - of which PAS25 is the first listed.
NCT03206112 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03206112 about?
NCT03206112 is a clinical study titled "Loss of Depotentiation in Focal Dystonia". Background Focal dystonia is a brain disorder. It affects a muscle or muscles in a specific part of the body. Researchers think it may be related to excessive training or practice. They want to know more about how much training might trigger focal dystonia. Objectives: To study why people develop...
What is the current status of trial NCT03206112?
This trial is currently terminated. The enrollment target is 6 participants. The study started on 2017-09-20. Estimated completion is 2020-04-09.
What interventions are being tested in trial NCT03206112?
The interventions under investigation include: PAS25 (OTHER), PAS10 (OTHER), PAS25-cTBS150 (OTHER).
Who is sponsoring clinical trial NCT03206112?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
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