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NCT03204955 · ClinicalTrials.gov registry record · Phase 1
A Low ChloridE hyperTonic Solution for Brain Edema
A Phase 1 study, sponsored by Emory University.
- Completed
- Registry status
- Phase 1
- Development phase
- 59
- Enrollment target
NCT03204955: Completed Phase 1 study, sponsored by Emory University.
NCT03204955 is a Phase 1 study that has completed, run by Emory University. The registered enrollment target is 59 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03204955, a Phase 1 study, has completed, sponsored by Emory University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 59 participants
- Enrollment target
Study Summary
This pilot study will compare the two hypertonic solutions currently used for subarachnoid hemorrhage (SAH) - related complications and to determine if the reduction of chloride load is safer, and as efficacious as the classic hypertonic solution.
Primary Outcome
Serum chloride levels will be measured as part of standard of care. Difference between serum chloride level on randomization day and the peak afterwards will be calculated.
Interventions
- DRUG Sodium chloride /sodium acetate (16.4%)
- DRUG Sodium chloride (23.4%)
- DRUG PlasmaLyte
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 59 participants |
| Start Date | 2017-06-28 |
| Est. Completion | 2018-09-30 |
| Phase | Phase 1 |
What the finished NCT03204955 record still lists
NCT03204955 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 59 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.
The record links to 0 conditions, and to 3 interventions - of which Sodium chloride /sodium acetate (16.4%) is the first listed.
NCT03204955 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03204955 about?
NCT03204955 is a clinical study titled "A Low ChloridE hyperTonic Solution for Brain Edema". This pilot study will compare the two hypertonic solutions currently used for subarachnoid hemorrhage (SAH) - related complications and to determine if the reduction of chloride load is safer, and as efficacious as the classic hypertonic solution.
What is the current status of trial NCT03204955?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 59 participants. The study started on 2017-06-28. Estimated completion is 2018-09-30.
What interventions are being tested in trial NCT03204955?
The interventions under investigation include: Sodium chloride /sodium acetate (16.4%) (DRUG), Sodium chloride (23.4%) (DRUG), PlasmaLyte (DRUG).
Who is sponsoring clinical trial NCT03204955?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03204955's enrollment target sits among peer trials
59 895th of 2000 higher than 1,106 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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