Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03202914 · ClinicalTrials.gov registry record · NA
Metabolomics for Identifying Biomarkers of Dietary Intake and Kidney Disease Progression
A NA study of Dietary Modification and Kidney Diseases, Chronic, sponsored by Johns Hopkins Bloomberg School of Public Health.
- Completed
- Registry status
- NA
- Development phase
- 840
- Enrollment target
- 1
- Study location
NCT03202914: Completed NA study of Dietary Modification and Kidney Diseases, Chronic, sponsored by Johns Hopkins Bloomberg School of Public Health.
NCT03202914 is a NA study of Dietary Modification and Kidney Diseases, Chronic that has completed, run by Johns Hopkins Bloomberg School of Public Health. The registered enrollment target is 840 participants, above the 69-participant average among 5 other Dietary Modification trials with a reported enrollment target (1117% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03202914, a NA study of Dietary Modification and Kidney Diseases, Chronic, has completed, sponsored by Johns Hopkins Bloomberg School of Public Health.
- COMPLETED
- Registry status
- NA
- Development phase
- 840 participants
- Enrollment target
- 1
- Study location
Study Summary
The present record represents a secondary data analysis of the Modification of Diet in Renal Disease (MDRD) Study. For this analysis, the MDRD study data and specimens were retrieved from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Central Repository. A global, untargeted, metabolomic profile was used to investigate biomarkers of dietary intake as well as biomarkers of kidney disease progression.
Primary Outcome
Metabolites were measured using a global, untargeted, metabolomic platform in serum specimens collected at the 12 month follow-up visit in the MDRD Study. Reverse phase, untargeted ultra-performance liquid chromatography tandem mass spectrometry quantification was used to measure metabolites. Peaks were quantified by calculating the area under the curve. Data were normalized to account for day-to-day instrumental variation. Compounds were identified by comparison to a library of purified standar
Conditions Studied
Interventions
- BEHAVIORAL Usual protein and phosphorus diet
- BEHAVIORAL Low protein and phosphorus diet
- BEHAVIORAL Very low protein and phosphorus
Study Locations (1)
Maryland
- Johns Hopkins Bloomberg School of Public Health - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 840 participants |
| Start Date | 1988-10 |
| Est. Completion | 2016-01 |
| Phase | NA |
What the finished NCT03202914 record still lists
NCT03202914 is an interventional study that assigns participants to a tested intervention. The registered 840 participants enrollment target is mid-sized for trials with a published cap, above the 69-participant average among 5 other Dietary Modification trials with a reported enrollment target (1117% higher).
The record links to 2 conditions, with Dietary Modification appearing as the primary indexed condition, and to 3 interventions - of which Usual protein and phosphorus diet is the first listed.
NCT03202914 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT03202914 about?
NCT03202914 is a clinical study titled "Metabolomics for Identifying Biomarkers of Dietary Intake and Kidney Disease Progression". The present record represents a secondary data analysis of the Modification of Diet in Renal Disease (MDRD) Study. For this analysis, the MDRD study data and specimens were retrieved from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Central Repository. A global, untar...
What is the current status of trial NCT03202914?
This trial is currently completed. It is a NA study. The enrollment target is 840 participants. The study started on 1988-10. Estimated completion is 2016-01.
What conditions does trial NCT03202914 study?
This clinical trial studies the following conditions: Dietary Modification, Kidney Diseases, Chronic.
What interventions are being tested in trial NCT03202914?
The interventions under investigation include: Usual protein and phosphorus diet (BEHAVIORAL), Low protein and phosphorus diet (BEHAVIORAL), Very low protein and phosphorus (BEHAVIORAL).
Who is sponsoring clinical trial NCT03202914?
This trial is sponsored by Johns Hopkins Bloomberg School of Public Health, which has 187 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03202914 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Dietary Modification
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Gut Flora Metabolite Reduction After Dietary Intervention (GRADY)
RECRUITING · NA
-
Nutricity: A Pilot Study to Improve Parental Nutrition Literacy
COMPLETED · NA
-
Spinal Cord Injury Exercise and Nutrition Conceptual Engagement
COMPLETED · NA
-
CARNIVAL Study: Gut Flora Dependent Metabolism of Dietary CARNItine and Phosphatidylcholine and cardioVAscuLar Disease
ACTIVE NOT RECRUITING · Early Phase 1
-
Resistant Maltodextrin for Gut Microbiome in Parkinson's Disease: Safety and Tolerability Study
ACTIVE NOT RECRUITING · Phase 2
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04831580 · 840 participants · NA
A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer
- NCT04976881 · 840 participants · NA
Promoting Preconception Care and Diabetes Self-Management Among Reproductive-Aged Women With Diabetes
- NCT04985903 · 840 participants · NA
Baby Steps III: Testing a Clinician and Patient Intervention to Promote Smoking Cessation Among Pregnant Women
- NCT05384626 · 840 participants · Phase 1
A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia