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NCT03189030 · ClinicalTrials.gov registry record · Phase 1
Study of Personalized Immunotherapy in Adults With Metastatic Colorectal Cancer
A Phase 1 study, sponsored by Aduro Biotech.
- Terminated
- Registry status
- Phase 1
- Development phase
- 28
- Enrollment target
NCT03189030: Clinical Trial Phase 1 study, sponsored by Aduro Biotech.
NCT03189030 is a Phase 1 study that was terminated before completion, run by Aduro Biotech. The registered enrollment target is 28 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03189030, a Phase 1 study, was terminated before completion, sponsored by Aduro Biotech.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 28 participants
- Enrollment target
Study Summary
This study will evaluate the safety and tolerability of a personalized live, attenuated, double-deleted Listeria monocytogenes (pLADD) treatment in adults with metastatic colorectal cancer.
Primary Outcome
Number of patients with treatment-related adverse events as assessed by CTCAE v 4.0
Interventions
- BIOLOGICAL pLADD
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2017-05-02 |
| Est. Completion | 2020-09-02 |
| Phase | Phase 1 |
Why NCT03189030 stopped before completion
NCT03189030 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower).
The record links to 0 conditions, and to 1 intervention - of which pLADD is the first listed.
NCT03189030 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03189030 about?
NCT03189030 is a clinical study titled "Study of Personalized Immunotherapy in Adults With Metastatic Colorectal Cancer". This study will evaluate the safety and tolerability of a personalized live, attenuated, double-deleted Listeria monocytogenes (pLADD) treatment in adults with metastatic colorectal cancer.
What is the current status of trial NCT03189030?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2017-05-02. Estimated completion is 2020-09-02.
What interventions are being tested in trial NCT03189030?
The interventions under investigation include: pLADD (BIOLOGICAL).
Who is sponsoring clinical trial NCT03189030?
This trial is sponsored by Aduro Biotech, which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03189030's enrollment target sits among peer trials
28 1447th of 2000 higher than 538 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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