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NCT03187977 · ClinicalTrials.gov registry record · NA
Cognitive Intervention at the End of Therapy for Survivors of Childhood ALL Treated on TOTXVI
A NA study, sponsored by St. Jude Children's Research Hospital.
- Completed
- Registry status
- NA
- Development phase
- 50
- Enrollment target
NCT03187977: Completed NA study, sponsored by St. Jude Children's Research Hospital.
NCT03187977 is a NA study that has completed, run by St. Jude Children's Research Hospital. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03187977, a NA study, has completed, sponsored by St. Jude Children's Research Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
Study Summary
Computer-based cognitive training has been found to be helpful for improving attention and working memory in pediatric and adult patients with existing cognitive difficulties. A previous study was conducted at St. Jude Children's Research Hospital with survivors of childhood cancer who were experiencing difficulties with attention and/or working memory. Findings from that study indicated that the use of Cogmed, computer-based cognitive training, is effective in improving attention and working memory in survivors. Researchers want to learn whether Cogmed intervention completed at the end of therapy for acute lymphoblastic leukemia will be effective for all survivors (i.e., regardless of whether they have existing difficulties). PRIMARY OBJECTIVES: * To evaluate the overall participation rate in a randomized, standard-of-care controlled trial of computerized cognitive intervention administered at the end of TOTXVI therapy. * To estimate the study completion rate in a randomized, standard-of-care controlled trial of computerized cognitive intervention administered at the end of TOTXVI therapy. * To estimate the compliance rate for participants randomized to the intervention arm of a computerized cognitive intervention administered at the end of TOTXVI therapy. * To estimate the standard deviation for the overall cohort on a measure of working memory. * To use neuroimaging data collected in the context of the Total Therapy XVI trial to explore candidate biomarkers predictive of response to the computerized cognitive intervention.
Primary Outcome
The magnitude and standard deviation of pre- to post-change in Spatial Span Backward will be estimated for each group and for the overall group.
Interventions
- BEHAVIORAL Cognitive training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2017-08-03 |
| Est. Completion | 2021-10-13 |
| Phase | NA |
What the finished NCT03187977 record still lists
NCT03187977 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 1 intervention - of which Cognitive training is the first listed.
NCT03187977 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03187977 about?
NCT03187977 is a clinical study titled "Cognitive Intervention at the End of Therapy for Survivors of Childhood ALL Treated on TOTXVI". Computer-based cognitive training has been found to be helpful for improving attention and working memory in pediatric and adult patients with existing cognitive difficulties. A previous study was conducted at St. Jude Children's Research Hospital with survivors of childhood cancer who were experien...
What is the current status of trial NCT03187977?
This trial is currently completed. It is a NA study. The enrollment target is 50 participants. The study started on 2017-08-03. Estimated completion is 2021-10-13.
What interventions are being tested in trial NCT03187977?
The interventions under investigation include: Cognitive training (BEHAVIORAL).
Who is sponsoring clinical trial NCT03187977?
This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03187977's enrollment target sits among peer trials
50 1279th of 2000 higher than 622 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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