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NCT03187106 · ClinicalTrials.gov registry record · Phase 1

Prophylactic Antibiotics After Cesarean

A Phase 1 study, sponsored by The University of Texas Medical Branch, Galveston.

Completed
Registry status
Phase 1
Development phase
321
Enrollment target

NCT03187106: Completed Phase 1 study, sponsored by The University of Texas Medical Branch, Galveston.

NCT03187106 is a Phase 1 study that has completed, run by The University of Texas Medical Branch, Galveston. The registered enrollment target is 321 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (435% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03187106, a Phase 1 study, has completed, sponsored by The University of Texas Medical Branch, Galveston.

COMPLETED
Registry status
Phase 1
Development phase
321 participants
Enrollment target

Study Summary

The purpose of this study is to determine if the addition of a 48-hour course of post-operative antibiotics to the recommended course of pre-operative antibiotics improves surgical site infection rate in patients who are obese and undergo Cesarean section after laboring.

Primary Outcome

Including superficial or deep incisional surgical site infection, endometritis, and other related infections, such as septic pelvic thrombophlebitis and abdominal or pelvic abscess

Interventions

  • DRUG Placebo
  • DRUG Metronidazole
  • DRUG Cephalexin

Trial Details

FieldValue
Enrollment Target 321 participants
Start Date 2017-08-01
Est. Completion 2023-07-21
Phase Phase 1

What the finished NCT03187106 record still lists

NCT03187106 is an interventional study that assigns participants to a tested intervention. The registered 321 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (435% higher).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT03187106 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03187106 about?

NCT03187106 is a clinical study titled "Prophylactic Antibiotics After Cesarean". The purpose of this study is to determine if the addition of a 48-hour course of post-operative antibiotics to the recommended course of pre-operative antibiotics improves surgical site infection rate in patients who are obese and undergo Cesarean section after laboring.

What is the current status of trial NCT03187106?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 321 participants. The study started on 2017-08-01. Estimated completion is 2023-07-21.

What interventions are being tested in trial NCT03187106?

The interventions under investigation include: Placebo (DRUG), Metronidazole (DRUG), Cephalexin (DRUG).

Who is sponsoring clinical trial NCT03187106?

This trial is sponsored by The University of Texas Medical Branch, Galveston, which has 203 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03187106's enrollment target sits among peer trials

321 111th of 2000 higher than 1,889 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03187106, the US trial registry maintained by the National Library of Medicine. NCT03187106 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.