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NCT03176316 · ClinicalTrials.gov registry record · Phase 4
The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus
A Phase 4 study, sponsored by Loyola University.
- Terminated
- Registry status
- Phase 4
- Development phase
- 53
- Enrollment target
NCT03176316: Clinical Trial Phase 4 study, sponsored by Loyola University.
NCT03176316 is a Phase 4 study that was terminated before completion, run by Loyola University. The registered enrollment target is 53 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03176316, a Phase 4 study, was terminated before completion, sponsored by Loyola University.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 53 participants
- Enrollment target
Study Summary
Postoperative ileus and opioid induced constipation are well-known post-operative complications. Previously, research has shown that using peripherally acting opioid antagonists can help alleviate the condition. There has not been a prospective study to investigate whether use of peripherally acting opioid antagonists are effective in preventing post-operative ileus in patients having spinal fusion surgeries.
Primary Outcome
We will monitor the patients' bowel movements and record the time to the first bowel movement in hours
Interventions
- DRUG Naloxone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 53 participants |
| Start Date | 2017-09-20 |
| Est. Completion | 2020-02-20 |
| Phase | Phase 4 |
Why NCT03176316 stopped before completion
NCT03176316 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 53 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 1 intervention - of which Naloxone is the first listed.
NCT03176316 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03176316 about?
NCT03176316 is a clinical study titled "The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus". Postoperative ileus and opioid induced constipation are well-known post-operative complications. Previously, research has shown that using peripherally acting opioid antagonists can help alleviate the condition. There has not been a prospective study to investigate whether use of peripherally acting...
What is the current status of trial NCT03176316?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 53 participants. The study started on 2017-09-20. Estimated completion is 2020-02-20.
What interventions are being tested in trial NCT03176316?
The interventions under investigation include: Naloxone (DRUG).
Who is sponsoring clinical trial NCT03176316?
This trial is sponsored by Loyola University, which has 92 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03176316's enrollment target sits among peer trials
53 1229th of 2000 higher than 768 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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