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NCT03171493 · ClinicalTrials.gov registry record · Phase 1

Trial of Intravesical Measles Virotherapy in Patients With Bladder Cancer Who Are Undergoing Radical Cystectomy

A Phase 1 study of Urothelial Carcinoma, sponsored by Vyriad.

Completed
Registry status
Phase 1
Development phase
8
Enrollment target
3
Study locations

NCT03171493 is a Phase 1 study of Urothelial Carcinoma that has completed, run by Vyriad. The registered enrollment target is 8 participants, below the 239-participant average among 85 other Urothelial Carcinoma trials with a reported enrollment target (97% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT03171493, a Phase 1 study of Urothelial Carcinoma, has completed, sponsored by Vyriad.

COMPLETED
Registry status
Phase 1
Development phase
8 participants
Enrollment target
3
Study locations

Study Summary

This is a Phase 1 study designed to test the tolerability and feasibility of intravesical therapy with an attenuated Measles virus (MV-NIS) in patients with urothelial carcinoma who are undergoing radical cystectomy but are ineligible or do not desire neoadjuvant chemotherapy.

Conditions Studied

Interventions

  • BIOLOGICAL MV-NIS

Study Locations (3)

Florida

  • University of Miami - Miami

Louisiana

  • Ochsner Health - New Orleans

Minnesota

  • Mayo Clinic - Rochester

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2018-07-20
Est. Completion 2023-05-12
Phase Phase 1

Sponsor

Vyriad

5 total trials

What the Registry Record Tells You About NCT03171493

The ClinicalTrials.gov registry entry for NCT03171493 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 8 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 239-participant average among 85 other Urothelial Carcinoma trials with a reported enrollment target (97% lower). The listed sponsor is Vyriad, which has 5 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Urothelial Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which MV-NIS is the first listed.

NCT03171493 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Florida, Louisiana, Minnesota.

Frequently Asked Questions

What is clinical trial NCT03171493 about?

NCT03171493 is a clinical study titled "Trial of Intravesical Measles Virotherapy in Patients With Bladder Cancer Who Are Undergoing Radical Cystectomy". This is a Phase 1 study designed to test the tolerability and feasibility of intravesical therapy with an attenuated Measles virus (MV-NIS) in patients with urothelial carcinoma who are undergoing radical cystectomy but are ineligible or do not desire neoadjuvant chemotherapy.

What is the current status of trial NCT03171493?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2018-07-20. Estimated completion is 2023-05-12.

What conditions does trial NCT03171493 study?

This clinical trial studies the following conditions: Urothelial Carcinoma.

What interventions are being tested in trial NCT03171493?

The interventions under investigation include: MV-NIS (BIOLOGICAL).

Who is sponsoring clinical trial NCT03171493?

This trial is sponsored by Vyriad, which has 5 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03171493 being conducted?

This trial has 3 study locations across Florida, Louisiana, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.