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NCT03171402 · ClinicalTrials.gov registry record

Astringency and Bitterness Perception

A clinical trial, sponsored by Purdue University.

Completed
Registry status
92
Enrollment target

NCT03171402: Completed study, sponsored by Purdue University.

NCT03171402 is a clinical trial that has completed, run by Purdue University. The registered enrollment target is 92 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03171402 has completed, sponsored by Purdue University.

COMPLETED
Registry status
92 participants
Enrollment target

Study Summary

The investigators are conducting a study to better understand how the average consumer differentiates between bitter and astringent sensations, both of which are typically unpleasant sensations characteristic of some healthy foods. Astringency is the dry/rough sensation elicited by foods such as green bananas and some wines. Although trained scientists can differentiate between these stimuli, untrained participants rate them similarly, despite their differences. This confusion has created additional barriers in understanding the mechanism of astringent perception, which is currently debated. Understanding how to design experiments where untrained participants can clearly evaluate both sensations will lay the foundation to better understand astringency. One mechanism that is believed to contribute to astringency is the interaction of astringent stimuli with salivary proteins. Interestingly, the salivary protein profile may be influenced by consumption of fruits and vegetables. Therefore, the investigators will evaluate how bitter and astringent perceptions differ among high and low consumers of fruits and vegetables by collecting saliva following exposure to the stimuli. This knowledge will inform approaches to increase the appeal of healthy food.

Primary Outcome

Liking and flavor intensity ratings on the general labeled magnitude scale

Interventions

  • DIAGNOSTIC_TEST Astringency and bitterness perception

Trial Details

FieldValue
Enrollment Target 92 participants
Start Date 2017-04-30
Est. Completion 2018-05-30
Purdue University

141 total trials

What the finished NCT03171402 record still lists

NCT03171402 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 92 participants, a relatively small participant target.

The record links to 0 conditions, and to 1 intervention - of which Astringency and bitterness perception is the first listed.

NCT03171402 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03171402 about?

NCT03171402 is a clinical study titled "Astringency and Bitterness Perception". The investigators are conducting a study to better understand how the average consumer differentiates between bitter and astringent sensations, both of which are typically unpleasant sensations characteristic of some healthy foods. Astringency is the dry/rough sensation elicited by foods such as gre...

What is the current status of trial NCT03171402?

This trial is currently completed. The enrollment target is 92 participants. The study started on 2017-04-30. Estimated completion is 2018-05-30.

What interventions are being tested in trial NCT03171402?

The interventions under investigation include: Astringency and bitterness perception (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT03171402?

This trial is sponsored by Purdue University, which has 141 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT03171402, the US trial registry maintained by the National Library of Medicine. NCT03171402 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.