Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03153111 · ClinicalTrials.gov registry record · Phase 2

A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease

A Phase 2 study, sponsored by Actelion.

Completed
Registry status
Phase 2
Development phase
143
Enrollment target

NCT03153111 is a Phase 2 study that has completed, run by Actelion. The registered enrollment target is 143 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03153111, a Phase 2 study, has completed, sponsored by Actelion.

COMPLETED
Registry status
Phase 2
Development phase
143 participants
Enrollment target

Study Summary

This is a study to evaluate whether macitentan is an effective and safe treatment for patients with heart failure with preserved ejection fraction (HFpEF) and pulmonary vascular disease. The primary objective is to evaluate whether macitentan 10 mg reduces N-terminal pro-brain natriuretic peptide (NT-pro-BNP) as compared to placebo in these patients.

Interventions

  • DRUG Placebo
  • DRUG Macitentan

Trial Details

FieldValue
Enrollment Target 143 participants
Start Date 2017-07-11
Est. Completion 2021-03-12
Phase Phase 2

Sponsor

Actelion

63 total trials

What the Registry Record Tells You About NCT03153111

The ClinicalTrials.gov registry entry for NCT03153111 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 143 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Actelion, which has 63 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT03153111 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03153111 about?

NCT03153111 is a clinical study titled "A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease". This is a study to evaluate whether macitentan is an effective and safe treatment for patients with heart failure with preserved ejection fraction (HFpEF) and pulmonary vascular disease. The primary objective is to evaluate whether macitentan 10 mg reduces N-terminal pro-brain natriuretic peptide (...

What is the current status of trial NCT03153111?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 143 participants. The study started on 2017-07-11. Estimated completion is 2021-03-12.

What interventions are being tested in trial NCT03153111?

The interventions under investigation include: Placebo (DRUG), Macitentan (DRUG).

Who is sponsoring clinical trial NCT03153111?

This trial is sponsored by Actelion, which has 63 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.