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NCT03149172 · ClinicalTrials.gov registry record · NA

Comparison of Post Tooth Extraction Healing Using Different Xenograft Materials

A NA study, sponsored by Tufts University.

Completed
Registry status
NA
Development phase
25
Enrollment target

NCT03149172: Completed NA study, sponsored by Tufts University.

NCT03149172 is a NA study that has completed, run by Tufts University. The registered enrollment target is 25 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03149172, a NA study, has completed, sponsored by Tufts University.

COMPLETED
Registry status
NA
Development phase
25 participants
Enrollment target

Study Summary

The purpose of this pilot study is to conduct a interventional prospective clinical trial to evaluate the efficacy of three different xenografts for ridge preservation by comparing the quality of newly formed bone using histomorphometric and micro CT analysis.The three xenograft materials under investigation are Bio-Oss® (bovine derived xenograft), Equimatrix® (equine derived xenograft), and Endobon® (bovine derived xenograft). There are no prospective studies comparing the effectiveness of these three materials, Bio-Oss®, Endobon® and Equimatrix®, when placed in extraction sockets. Participants will be recruited from patients in the TUSDM clinics that require extraction of single rooted non-molar tooth and are treatment planned to receive dental implants in the future. Participants will be randomized to receive one of the three xenograft materials after tooth extraction. The percentage of newly formed bone and bone density will be compared between the three materials 4-6 months after ridge preservation.

Primary Outcome

Histomorphometric determination of % new bone formation

Interventions

  • DEVICE Bio-Oss®
  • DEVICE Equimatrix®
  • DEVICE Endobon®

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2014-10-20
Est. Completion 2016-12-07
Phase NA
Tufts University

163 total trials

What the finished NCT03149172 record still lists

NCT03149172 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 3 interventions - of which Bio-Oss® is the first listed.

NCT03149172 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03149172 about?

NCT03149172 is a clinical study titled "Comparison of Post Tooth Extraction Healing Using Different Xenograft Materials". The purpose of this pilot study is to conduct a interventional prospective clinical trial to evaluate the efficacy of three different xenografts for ridge preservation by comparing the quality of newly formed bone using histomorphometric and micro CT analysis.The three xenograft materials under inve...

What is the current status of trial NCT03149172?

This trial is currently completed. It is a NA study. The enrollment target is 25 participants. The study started on 2014-10-20. Estimated completion is 2016-12-07.

What interventions are being tested in trial NCT03149172?

The interventions under investigation include: Bio-Oss® (DEVICE), Equimatrix® (DEVICE), Endobon® (DEVICE).

Who is sponsoring clinical trial NCT03149172?

This trial is sponsored by Tufts University, which has 163 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03149172's enrollment target sits among peer trials

25 1712th of 2000 higher than 265 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03149172, the US trial registry maintained by the National Library of Medicine. NCT03149172 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.