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NCT03142815 · ClinicalTrials.gov registry record
Aortic-Radial Pressure Gradients Post CPB
A clinical trial, sponsored by University of Iowa.
- Completed
- Registry status
- 90
- Enrollment target
NCT03142815: Completed study, sponsored by University of Iowa.
NCT03142815 is a clinical trial that has completed, run by University of Iowa. The registered enrollment target is 90 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03142815 has completed, sponsored by University of Iowa.
- COMPLETED
- Registry status
- 90 participants
- Enrollment target
Study Summary
This study will examine whether pre-operative, non-invasive arterial stiffness measurements can be used to predict which patients will develop an aortic-to-radial pressure gradient after coronary artery bypass graft (CABG) surgery. A previous small study by Kanazawa, et al. demonstrated in patients who developed an aortic-to-radial pressure gradient after CABG surgery, the pulse wave velocity (PWV) was higher in the aorta and decreased when moving toward the radial artery. In the patients who did not develop a pressure gradient, the PWV started lower in the aorta and increased when moving towards the periphery. The purpose of this investigation is to examine whether pre-operative PWV measurements can be used to identify patients who will develop an aortic to radial pressure gradient after CABG surgery. Applanation tonometry will be performed on the right carotid and femoral arteries to assess carotid-femoral pulse wave velocity, a surrogate for aortic stiffness. (SphygmoCor system, AtCor Medical, Sydney, Australia). The measurement will be obtained before induction of general anesthesia in the presurgical area. Also in the presurgical area, a non-invasive cardiac output (CO) measurement will be obtained by using the ICON Device (Osypka Medical, La Jolla, California). This CO value will be used to compare to the CO values obtained invasively in the operating room.
Primary Outcome
The study is aimed to compare cfPWV between patients who develop an aortic-to-radial pressure gradient after coronary artery bypass and those who don't who are undergoing coronary artery bypass graft surgery. Arterial stiffness will be measured by pulse wave velocity (m/s) with a SphygmoCor® device (Atcor, Sydney, Australia)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2017-06-12 |
| Est. Completion | 2020-03-17 |
What the finished NCT03142815 record still lists
NCT03142815 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 90 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT03142815 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03142815 about?
NCT03142815 is a clinical study titled "Aortic-Radial Pressure Gradients Post CPB". This study will examine whether pre-operative, non-invasive arterial stiffness measurements can be used to predict which patients will develop an aortic-to-radial pressure gradient after coronary artery bypass graft (CABG) surgery. A previous small study by Kanazawa, et al. demonstrated in patients ...
What is the current status of trial NCT03142815?
This trial is currently completed. The enrollment target is 90 participants. The study started on 2017-06-12. Estimated completion is 2020-03-17.
Who is sponsoring clinical trial NCT03142815?
This trial is sponsored by University of Iowa, which has 228 total clinical trials registered on ClinicalTrials.gov.
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