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NCT03142763 · ClinicalTrials.gov registry record · NA
Assessment of TMAO Formation With Egg Intake Versus Choline Supplement in a Healthy Population
A NA study of Cardiovascular Risk Factor, sponsored by University of Connecticut.
- Completed
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT03142763: Completed NA study of Cardiovascular Risk Factor, sponsored by University of Connecticut.
NCT03142763 is a NA study of Cardiovascular Risk Factor that has completed, run by University of Connecticut. The registered enrollment target is 30 participants, below the 3,067-participant average among 31 other Cardiovascular Risk Factor trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03142763, a NA study of Cardiovascular Risk Factor, has completed, sponsored by University of Connecticut.
- COMPLETED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of this study is to determine the effects of consuming either 3 eggs per day as compared to a daily choline supplement (choline bitartrate, 397.5 mg choline/day) on plasma concentrations of High Density Lipoprotein-cholesterol (HDL-C), trimethylamine N-oxide (TMAO), and other biomarkers of cardiovascular disease risk in young, healthy individuals. The goal is to determine if choline given as phosphatidylcholine (eggs) will lead to a different TMAO response when compared to choline in free supplemental form.
Primary Outcome
Using plasma form each participant, an automated spectrophotometer is able to analyze at once plasma lipids \[total colesterol, triglycerides, HDL (mg/dL)\], glucose (mg/dL), CRP (mg/dL, and liver enzymes \[alanine aminotransferase and aspartate aminotransferase (U/L)\].
Conditions Studied
Interventions
- OTHER Eggs
- DIETARY_SUPPLEMENT Choline Supplement
Study Locations (1)
Connecticut
- University of Connecticut - Storrs
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2017-01 |
| Est. Completion | 2018-12-31 |
| Phase | NA |
What the finished NCT03142763 record still lists
NCT03142763 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 3,067-participant average among 31 other Cardiovascular Risk Factor trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Cardiovascular Risk Factor appearing as the primary indexed condition, and to 2 interventions - of which Eggs is the first listed.
NCT03142763 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT03142763 about?
NCT03142763 is a clinical study titled "Assessment of TMAO Formation With Egg Intake Versus Choline Supplement in a Healthy Population". The objective of this study is to determine the effects of consuming either 3 eggs per day as compared to a daily choline supplement (choline bitartrate, 397.5 mg choline/day) on plasma concentrations of High Density Lipoprotein-cholesterol (HDL-C), trimethylamine N-oxide (TMAO), and other biomarker...
What is the current status of trial NCT03142763?
This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2017-01. Estimated completion is 2018-12-31.
What conditions does trial NCT03142763 study?
This clinical trial studies the following conditions: Cardiovascular Risk Factor.
What interventions are being tested in trial NCT03142763?
The interventions under investigation include: Eggs (OTHER), Choline Supplement (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT03142763?
This trial is sponsored by University of Connecticut, which has 107 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03142763 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiovascular Risk Factor
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03142763's enrollment target sits among peer trials
30 25th of 31 higher than 6 of 31 other Cardiovascular Risk Factor trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiovascular Risk Factor trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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