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NCT03111017 · ClinicalTrials.gov registry record · NA
Mechanisms and Management of Exercise Intolerance in Older Heart Failure Patients
A NA study, sponsored by The University of Texas at Arlington.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
NCT03111017 is a NA study that has completed, run by The University of Texas at Arlington. The registered enrollment target is 12 participants.
The verdict
NCT03111017, a NA study, has completed, sponsored by The University of Texas at Arlington.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
Study Summary
Heart failure with preserved ejection fraction (HFpEF) is the fastest growing form of heart failure with a high morbidity and mortality rate, and is associated with severe exercise intolerance. The mechanisms responsible for the reduced exercise tolerance remain poorly understood. The investigators propose a novel paradigm shift, focusing on peripheral limitations to exercise. In particular, the investigators will test the hypothesis that muscle sympathetic nerve activity (MSNA) is elevated in older HFpEF patients compared to healthy controls, and is associated with reduced exercise tolerance. The investigators will also test whether 16-weeks of exercise training will lower MSNA compared to attention control, and correlate with improved exercise tolerance in older HFpEF patients.
Interventions
- OTHER Exercise Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2017-04-17 |
| Est. Completion | 2019-12-12 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03111017
The ClinicalTrials.gov registry entry for NCT03111017 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The University of Texas at Arlington, which has 32 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Exercise Training is the first listed.
NCT03111017 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03111017 about?
NCT03111017 is a clinical study titled "Mechanisms and Management of Exercise Intolerance in Older Heart Failure Patients". Heart failure with preserved ejection fraction (HFpEF) is the fastest growing form of heart failure with a high morbidity and mortality rate, and is associated with severe exercise intolerance. The mechanisms responsible for the reduced exercise tolerance remain poorly understood. The investigators ...
What is the current status of trial NCT03111017?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2017-04-17. Estimated completion is 2019-12-12.
What interventions are being tested in trial NCT03111017?
The interventions under investigation include: Exercise Training (OTHER).
Who is sponsoring clinical trial NCT03111017?
This trial is sponsored by The University of Texas at Arlington, which has 32 total clinical trials registered on ClinicalTrials.gov.
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