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NCT03110926 · ClinicalTrials.gov registry record · Phase 2
Induction Chemotherapy for Locally Advanced Esophageal Cancer
A Phase 2 study of Esophageal Carcinoma, sponsored by University of Rochester.
- Active
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT03110926: Active Phase 2 study of Esophageal Carcinoma, sponsored by University of Rochester.
NCT03110926 is a Phase 2 study of Esophageal Carcinoma that is active but no longer recruiting, run by University of Rochester. The registered enrollment target is 40 participants, below the 2,385-participant average among 17 other Esophageal Carcinoma trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03110926, a Phase 2 study of Esophageal Carcinoma, is active but no longer recruiting, sponsored by University of Rochester.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Evaluate mFOLFOX6 (5-Fluorouracil, Leucovorin and Oxaliplatin) chemotherapy as induction treatment prior to standard neoadjuvant chemoradiation to decrease the rate of distant recurrence among patients with locally advanced esophageal cancer.
Primary Outcome
Evaluate the 2-year disease-free survival rate in patients who receive induction chemotherapy with mFOLFOX6 followed by standard chemoradiation and surgery.
Conditions Studied
Interventions
- COMBINATION_PRODUCT Chemoradiation
- DRUG mFOLFOX6
Study Locations (1)
New York
- University of Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2017-06-19 |
| Est. Completion | 2027-05-31 |
| Phase | Phase 2 |
What the registry record for NCT03110926 still lists
NCT03110926 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 2,385-participant average among 17 other Esophageal Carcinoma trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Esophageal Carcinoma appearing as the primary indexed condition, and to 2 interventions - of which Chemoradiation is the first listed.
NCT03110926 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT03110926 about?
NCT03110926 is a clinical study titled "Induction Chemotherapy for Locally Advanced Esophageal Cancer". Evaluate mFOLFOX6 (5-Fluorouracil, Leucovorin and Oxaliplatin) chemotherapy as induction treatment prior to standard neoadjuvant chemoradiation to decrease the rate of distant recurrence among patients with locally advanced esophageal cancer.
What is the current status of trial NCT03110926?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2017-06-19. Estimated completion is 2027-05-31.
What conditions does trial NCT03110926 study?
This clinical trial studies the following conditions: Esophageal Carcinoma.
What interventions are being tested in trial NCT03110926?
The interventions under investigation include: Chemoradiation (COMBINATION_PRODUCT), mFOLFOX6 (DRUG).
Who is sponsoring clinical trial NCT03110926?
This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03110926 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Esophageal Carcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03110926's enrollment target sits among peer trials
40 13th of 17 higher than 5 of 17 other Esophageal Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Esophageal Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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