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NCT03107416 · ClinicalTrials.gov registry record · Phase 1

Delivering a Diuretic Into the Liver Artery Followed by Plugging up the Artery to Starve Out Liver Cancer Cells

A Phase 1 study of Unresectable Hepatocellular Carcinoma, sponsored by Memorial Sloan Kettering Cancer Center.

Active
Registry status
Phase 1
Development phase
30
Enrollment target
5
Study locations

NCT03107416 is a Phase 1 study of Unresectable Hepatocellular Carcinoma that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 30 participants, below the 84-participant average among 12 other Unresectable Hepatocellular Carcinoma trials with a reported enrollment target (64% lower). The trial reports 5 study locations across 2 states.

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The verdict

NCT03107416, a Phase 1 study of Unresectable Hepatocellular Carcinoma, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
30 participants
Enrollment target
5
Study locations

Study Summary

The purpose of this study is to test the safety of Bumetanide , at different doses to find out what effects, if any, it has on people who undergo tumor TAE as part of their regular care. Bumetanide is a commonly used medication to reduce the amount of water in the body.

Interventions

  • DRUG Bumetanide
  • PROCEDURE Hepatic artery embolization (HAE)

Study Locations (5)

New Jersey

  • Memorial Sloan Kettering Basking Ridge (Consent and follow-up only) - Basking Ridge
  • Memorial Sloan Kettering Monmouth (Consent and follow-up only) - Middletown
  • Memorial Sloan Kettering Bergen (Consent and follow-up only) - Montvale

New York

  • Memorial Sloan Kettering Westchester (Consent and follow-up only) - Harrison
  • Memorial Sloan Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2017-04-05
Est. Completion 2026-04-05
Phase Phase 1

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT03107416

The ClinicalTrials.gov registry entry for NCT03107416 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 84-participant average among 12 other Unresectable Hepatocellular Carcinoma trials with a reported enrollment target (64% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Unresectable Hepatocellular Carcinoma appearing as the primary indexed condition, and to 2 interventions - of which Bumetanide is the first listed.

NCT03107416 reports 5 study locations spanning 2 distinct geographic areas - top geographies include New Jersey, New York.

Frequently Asked Questions

What is clinical trial NCT03107416 about?

NCT03107416 is a clinical study titled "Delivering a Diuretic Into the Liver Artery Followed by Plugging up the Artery to Starve Out Liver Cancer Cells". The purpose of this study is to test the safety of Bumetanide , at different doses to find out what effects, if any, it has on people who undergo tumor TAE as part of their regular care. Bumetanide is a commonly used medication to reduce the amount of water in the body.

What is the current status of trial NCT03107416?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2017-04-05. Estimated completion is 2026-04-05.

What conditions does trial NCT03107416 study?

This clinical trial studies the following conditions: Unresectable Hepatocellular Carcinoma.

What interventions are being tested in trial NCT03107416?

The interventions under investigation include: Bumetanide (DRUG), Hepatic artery embolization (HAE) (PROCEDURE).

Who is sponsoring clinical trial NCT03107416?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03107416 being conducted?

This trial has 5 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.