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NCT03091257 · ClinicalTrials.gov registry record · Phase 1

A Study of Dabrafenib and/or Trametinib in Patients With Relapsed and/or Refractory Multiple Myeloma

A Phase 1 study of Multiple Myeloma, sponsored by Massachusetts General Hospital.

Active
Registry status
Phase 1
Development phase
30
Enrollment target
2
Study locations

NCT03091257: Active Phase 1 study of Multiple Myeloma, sponsored by Massachusetts General Hospital.

NCT03091257 is a Phase 1 study of Multiple Myeloma that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 30 participants, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (95% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03091257, a Phase 1 study of Multiple Myeloma, is active but no longer recruiting, sponsored by Massachusetts General Hospital.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
30 participants
Enrollment target
2
Study locations

Study Summary

This research study is studying a targeted therapy as a possible treatment for multiple myeloma. The names of the study drugs involved in this study are: * Trametinib * Dabrafenib

Conditions Studied

Interventions

  • DRUG Trametinib
  • DRUG Dabrafenib

Study Locations (2)

Massachusetts

  • Massachusetts General Hospital - Boston

Michigan

  • Karmanos Cancer Institute - Detroit

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2017-06-21
Est. Completion 2026-09-15
Phase Phase 1

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT03091257

The ClinicalTrials.gov registry entry for NCT03091257 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 547-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (95% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Myeloma appearing as the primary indexed condition, and to 2 interventions - of which Trametinib is the first listed.

NCT03091257 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Massachusetts, Michigan.

Frequently Asked Questions

What is clinical trial NCT03091257 about?

NCT03091257 is a clinical study titled "A Study of Dabrafenib and/or Trametinib in Patients With Relapsed and/or Refractory Multiple Myeloma". This research study is studying a targeted therapy as a possible treatment for multiple myeloma. The names of the study drugs involved in this study are: * Trametinib * Dabrafenib

What is the current status of trial NCT03091257?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2017-06-21. Estimated completion is 2026-09-15.

What conditions does trial NCT03091257 study?

This clinical trial studies the following conditions: Multiple Myeloma.

What interventions are being tested in trial NCT03091257?

The interventions under investigation include: Trametinib (DRUG), Dabrafenib (DRUG).

Who is sponsoring clinical trial NCT03091257?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03091257 being conducted?

This trial has 2 study locations across Massachusetts, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.