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NCT03089515 · ClinicalTrials.gov registry record · NA
Small Airway Chronic Obstructive Disease Syndrome Following Exposure to WTC Dust
A NA study, sponsored by NYU Langone Health.
- Completed
- Registry status
- NA
- Development phase
- 46
- Enrollment target
NCT03089515: Completed NA study, sponsored by NYU Langone Health.
NCT03089515 is a NA study that has completed, run by NYU Langone Health. The registered enrollment target is 46 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03089515, a NA study, has completed, sponsored by NYU Langone Health.
- COMPLETED
- Registry status
- NA
- Development phase
- 46 participants
- Enrollment target
Study Summary
Many "Survivors" in the World Trade Center (WTC) clinical program have a clinical syndrome characterized by chronic obstruction in small airways and persistence of lower respiratory symptoms despite therapy. This study will test the hypothesis that persistent symptoms in WTC "Survivors" are associated with abnormal small airways whose dysfunction is amplified during exercise and is associated with biologic evidence of inflammation and remodeling. The results from this study will have important treatment implications for our WTC population with potential applicability to larger populations with either inhalational lung injury and/or airway diseases such as asthma and chronic obstructive pulmonary disease.
Primary Outcome
functional impairment at rest and with increased respiratory frequency (spirometry and forced oscillation techniques; FOT).
Interventions
- OTHER Cardio-Pulmonary Exercise Testing (CPET)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2017-09-07 |
| Est. Completion | 2021-09-01 |
| Phase | NA |
What the finished NCT03089515 record still lists
NCT03089515 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which Cardio-Pulmonary Exercise Testing (CPET) is the first listed.
NCT03089515 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03089515 about?
NCT03089515 is a clinical study titled "Small Airway Chronic Obstructive Disease Syndrome Following Exposure to WTC Dust". Many "Survivors" in the World Trade Center (WTC) clinical program have a clinical syndrome characterized by chronic obstruction in small airways and persistence of lower respiratory symptoms despite therapy. This study will test the hypothesis that persistent symptoms in WTC "Survivors" are associat...
What is the current status of trial NCT03089515?
This trial is currently completed. It is a NA study. The enrollment target is 46 participants. The study started on 2017-09-07. Estimated completion is 2021-09-01.
What interventions are being tested in trial NCT03089515?
The interventions under investigation include: Cardio-Pulmonary Exercise Testing (CPET) (OTHER).
Who is sponsoring clinical trial NCT03089515?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03089515's enrollment target sits among peer trials
46 1402nd of 2000 higher than 590 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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