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NCT03088592 · ClinicalTrials.gov registry record · NA
Electrophysiological Recordings of Deep Brain Stimulation in the Basal Ganglia
A NA study, sponsored by St. Joseph's Hospital and Medical Center, Phoenix.
- Completed
- Registry status
- NA
- Development phase
- 34
- Enrollment target
NCT03088592: Completed NA study, sponsored by St. Joseph's Hospital and Medical Center, Phoenix.
NCT03088592 is a NA study that has completed, run by St. Joseph's Hospital and Medical Center, Phoenix. The registered enrollment target is 34 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03088592, a NA study, has completed, sponsored by St. Joseph's Hospital and Medical Center, Phoenix.
- COMPLETED
- Registry status
- NA
- Development phase
- 34 participants
- Enrollment target
Study Summary
The pathology of Parkinson's disease (PD) and the mechanism of Deep Brain Stimulation surgery (DBS) are not completely understood. The recording data that is used routinely as part of the procedure to map the target structures, however, may be analyzed in order to better understand the neural network dynamics in PD. The purpose of the study is to perform simultaneous neural recordings from sub-cortical structures (e.g. subthalamic nucleus \[STN\] or globus pallidus internus \[GPi\]) and the cerebral cortex. These simultaneous recordings may provide insight in the pathology of PD and the mechanism of DBS. The researchers will also study the effects of anesthesia level on neuron synchronization . Recordings with micro-ECoG grid electrodes in the cortex show improved spatial resolution and these will be used to gain better understanding of cortical network dynamics and the synchronization with subcortical structures.
Primary Outcome
Simultaneous neural recordings from sub-cortical structures (e.g. subthalamic nucleus \[STN\] or globus pallidus internus \[GPi\]) and the cerebral cortex will be collected. Recordings include action potentials and local field potentials from sub-cortical structures while subdural microelectrocorticography grids will be used to record local field potential from the cerebral cortex. Time, frequency, and phase relationships between action potentials and local field potentials will also be studied
Interventions
- DEVICE Deep Brain Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2016-02-01 |
| Est. Completion | 2022-03 |
| Phase | NA |
What the finished NCT03088592 record still lists
NCT03088592 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Deep Brain Stimulation is the first listed.
NCT03088592 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03088592 about?
NCT03088592 is a clinical study titled "Electrophysiological Recordings of Deep Brain Stimulation in the Basal Ganglia". The pathology of Parkinson's disease (PD) and the mechanism of Deep Brain Stimulation surgery (DBS) are not completely understood. The recording data that is used routinely as part of the procedure to map the target structures, however, may be analyzed in order to better understand the neural networ...
What is the current status of trial NCT03088592?
This trial is currently completed. It is a NA study. The enrollment target is 34 participants. The study started on 2016-02-01. Estimated completion is 2022-03.
What interventions are being tested in trial NCT03088592?
The interventions under investigation include: Deep Brain Stimulation (DEVICE).
Who is sponsoring clinical trial NCT03088592?
This trial is sponsored by St. Joseph's Hospital and Medical Center, Phoenix, which has 44 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03088592's enrollment target sits among peer trials
34 1570th of 2000 higher than 427 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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