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NCT03086707 · ClinicalTrials.gov registry record · NA

Prefatory Study to Explore Changes in Nasal Mucociliary Clearance and to Standardize Nasal Scraping Procedure

A NA study, sponsored by Philip Morris Products S.A..

Completed
Registry status
NA
Development phase
14
Enrollment target

NCT03086707: Completed NA study, sponsored by Philip Morris Products S.A..

NCT03086707 is a NA study that has completed, run by Philip Morris Products S.A.. The registered enrollment target is 14 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03086707, a NA study, has completed, sponsored by Philip Morris Products S.A..

COMPLETED
Registry status
NA
Development phase
14 participants
Enrollment target

Study Summary

This study intends to evaluate the nasal mucociliary clearance (NMC) by determining the value obtained for saccharin transit time (STT) test over the course of 12 hours following a single cigarette use in adult smokers, to compare it relative to never smokers, and to examine the relationship between plasma nicotine levels and STT value in smokers and never smokers. Safety will also be monitored during the study. The planned maximum study duration for a single study participant from Screening through completion of study will be 33 days.

Primary Outcome

Before performing the test, each subject will spend approximately 15 minutes acclimatizing to the environment of the clinic. A 1-2 mm particle of saccharin will be placed under direct vision, approximately 1 cm behind the anterior end of the inferior turbinate. The position of the subject's head should be flexed approximately 10° by visual assessment. The saccharin transit time will be determined as the elapsed time in minutes and seconds from placement of the saccharin until the time the subje

Interventions

  • OTHER Cigarette

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2017-01-21
Est. Completion 2017-09-29
Phase NA
Philip Morris Products S.A.

11 total trials

What the finished NCT03086707 record still lists

NCT03086707 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which Cigarette is the first listed.

NCT03086707 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03086707 about?

NCT03086707 is a clinical study titled "Prefatory Study to Explore Changes in Nasal Mucociliary Clearance and to Standardize Nasal Scraping Procedure". This study intends to evaluate the nasal mucociliary clearance (NMC) by determining the value obtained for saccharin transit time (STT) test over the course of 12 hours following a single cigarette use in adult smokers, to compare it relative to never smokers, and to examine the relationship between...

What is the current status of trial NCT03086707?

This trial is currently completed. It is a NA study. The enrollment target is 14 participants. The study started on 2017-01-21. Estimated completion is 2017-09-29.

What interventions are being tested in trial NCT03086707?

The interventions under investigation include: Cigarette (OTHER).

Who is sponsoring clinical trial NCT03086707?

This trial is sponsored by Philip Morris Products S.A., which has 11 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03086707's enrollment target sits among peer trials

14 1909th of 2000 higher than 90 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03086707, the US trial registry maintained by the National Library of Medicine. NCT03086707 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.