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NCT03078127 · ClinicalTrials.gov registry record · NA
Researching the Effects of Airway Clearance Therapies in Cystic Fibrosis
A NA study, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT03078127: Completed NA study, sponsored by University of North Carolina, Chapel Hill.
NCT03078127 is a NA study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03078127, a NA study, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
This is a pilot study investigating the effectiveness and clinical efficacy of airway clearance therapy (ACT) in cystic fibrosis (CF). Enrolled subjects will undergo measurements of mucociliary clearance (MCC) and exhaled biomarkers at baseline and after 3 different forms of ACT: high frequency chest wall oscillatory vest, oscillatory positive expiratory pressure device, and whole-body vibration.
Primary Outcome
As described in the protocol, gamma scintigraphy was used to measure clearance of particles from the whole right lung region of interest over 274 minutes. The primary outcome for this study was the area under the particle clearance curve from time 0 to 274 minutes post-inhalation (normalized to time by dividing by 274) and expressed as a percent, representing total average rate of mucociliary clearance (MCC).
Interventions
- OTHER Baseline (Huff-Cough alone)
- DEVICE Oscillatory Positive Expiatory Pressure Device
- DEVICE Whole-Body Vibration Platform
- DEVICE High Frequency Chest Wall Oscillatory Vest
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2017-02-01 |
| Est. Completion | 2018-01-10 |
| Phase | NA |
What the finished NCT03078127 record still lists
NCT03078127 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 4 interventions - of which Baseline (Huff-Cough alone) is the first listed.
NCT03078127 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03078127 about?
NCT03078127 is a clinical study titled "Researching the Effects of Airway Clearance Therapies in Cystic Fibrosis". This is a pilot study investigating the effectiveness and clinical efficacy of airway clearance therapy (ACT) in cystic fibrosis (CF). Enrolled subjects will undergo measurements of mucociliary clearance (MCC) and exhaled biomarkers at baseline and after 3 different forms of ACT: high frequency ches...
What is the current status of trial NCT03078127?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2017-02-01. Estimated completion is 2018-01-10.
What interventions are being tested in trial NCT03078127?
The interventions under investigation include: Baseline (Huff-Cough alone) (OTHER), Oscillatory Positive Expiatory Pressure Device (DEVICE), Whole-Body Vibration Platform (DEVICE), High Frequency Chest Wall Oscillatory Vest (DEVICE).
Who is sponsoring clinical trial NCT03078127?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03078127's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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