Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03060642 · ClinicalTrials.gov registry record
The Microenvironment in Barrett's Esophagus
A clinical trial, sponsored by Columbia University.
- Completed
- Registry status
- 155
- Enrollment target
NCT03060642 is a clinical trial that has completed, run by Columbia University. The registered enrollment target is 155 participants.
The verdict
NCT03060642 has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- 155 participants
- Enrollment target
Study Summary
This study aims to elucidate the relationship between the microbiome, inflammation, and the microenvironment in Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC), with the end goal of developing a non-endoscopic testing strategy based on pathogenic factors to identify patients at highest risk for EAC. To accomplish this the investigators will enroll 100 patients with known BE (50 with dysplasia or EAC) and 50 subjects without BE undergoing upper endoscopy. Prior to endoscopy each subject will undergo three minimally invasive potential screening and surveillance tests: saliva (oral microbiome), breath test (exhaled volatile organic compounds), and tethered capsule sponge sampling (methylated DNA markers). The study will evaluate these novel tests in combination with clinical and anthropometric factors to describe an optimal strategy for BE screening and monitoring.
Interventions
- DEVICE Tethered capsule sponge
- DEVICE Electronic nose device
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 155 participants |
| Start Date | 2018-02-01 |
| Est. Completion | 2022-11-30 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03060642
The ClinicalTrials.gov registry entry for NCT03060642 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 155 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Tethered capsule sponge is the first listed.
NCT03060642 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03060642 about?
NCT03060642 is a clinical study titled "The Microenvironment in Barrett's Esophagus". This study aims to elucidate the relationship between the microbiome, inflammation, and the microenvironment in Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC), with the end goal of developing a non-endoscopic testing strategy based on pathogenic factors to identify patients at highest ...
What is the current status of trial NCT03060642?
This trial is currently completed. The enrollment target is 155 participants. The study started on 2018-02-01. Estimated completion is 2022-11-30.
What interventions are being tested in trial NCT03060642?
The interventions under investigation include: Tethered capsule sponge (DEVICE), Electronic nose device (DEVICE).
Who is sponsoring clinical trial NCT03060642?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.