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NCT03054298 · ClinicalTrials.gov registry record · Phase 1

CAR T Cells in Mesothelin Expressing Cancers

A Phase 1 study, sponsored by University of Pennsylvania.

Completed
Registry status
Phase 1
Development phase
65
Enrollment target

NCT03054298: Completed Phase 1 study, sponsored by University of Pennsylvania.

NCT03054298 is a Phase 1 study that has completed, run by University of Pennsylvania. The registered enrollment target is 65 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03054298, a Phase 1 study, has completed, sponsored by University of Pennsylvania.

COMPLETED
Registry status
Phase 1
Development phase
65 participants
Enrollment target

Study Summary

Phase I study to establish safety and feasibility of both intravenous administration and local delivery of lentiviral transduced huCART-meso cells with or without lymphodepletion.

Interventions

  • BIOLOGICAL huCART-meso cells

Trial Details

FieldValue
Enrollment Target 65 participants
Start Date 2017-04-06
Est. Completion 2024-07-30
Phase Phase 1
University of Pennsylvania

1,423 total trials

What the finished NCT03054298 record still lists

NCT03054298 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.

The record links to 0 conditions, and to 1 intervention - of which huCART-meso cells is the first listed.

NCT03054298 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03054298 about?

NCT03054298 is a clinical study titled "CAR T Cells in Mesothelin Expressing Cancers". Phase I study to establish safety and feasibility of both intravenous administration and local delivery of lentiviral transduced huCART-meso cells with or without lymphodepletion.

What is the current status of trial NCT03054298?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 65 participants. The study started on 2017-04-06. Estimated completion is 2024-07-30.

What interventions are being tested in trial NCT03054298?

The interventions under investigation include: huCART-meso cells (BIOLOGICAL).

Who is sponsoring clinical trial NCT03054298?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03054298's enrollment target sits among peer trials

65 798th of 2000 higher than 1,193 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03054298, the US trial registry maintained by the National Library of Medicine. NCT03054298 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.