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NCT03047993 · ClinicalTrials.gov registry record · Phase 1

Glutaminase Inhibitor CB-839 and Azacitidine in Treating Patients With Advanced Myelodysplastic Syndrome

A Phase 1 study, sponsored by M.D. Anderson Cancer Center.

Completed
Registry status
Phase 1
Development phase
28
Enrollment target

NCT03047993: Completed Phase 1 study, sponsored by M.D. Anderson Cancer Center.

NCT03047993 is a Phase 1 study that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 28 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03047993, a Phase 1 study, has completed, sponsored by M.D. Anderson Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
28 participants
Enrollment target

Study Summary

This phase I/II trial studies the side effects of glutaminase inhibitor CB-839 in combination with azacitidine in treating patients with myelodysplastic syndrome that has spread to other places in the body. Glutaminase inhibitor CB-839 and azacitidine may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Interventions

  • DRUG Azacitidine
  • DRUG Glutaminase Inhibitor CB-839

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2017-11-15
Est. Completion 2023-03-16
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT03047993

The ClinicalTrials.gov registry entry for NCT03047993 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Azacitidine is the first listed.

NCT03047993 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03047993 about?

NCT03047993 is a clinical study titled "Glutaminase Inhibitor CB-839 and Azacitidine in Treating Patients With Advanced Myelodysplastic Syndrome". This phase I/II trial studies the side effects of glutaminase inhibitor CB-839 in combination with azacitidine in treating patients with myelodysplastic syndrome that has spread to other places in the body. Glutaminase inhibitor CB-839 and azacitidine may stop the growth of tumor cells by blocking s...

What is the current status of trial NCT03047993?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2017-11-15. Estimated completion is 2023-03-16.

What interventions are being tested in trial NCT03047993?

The interventions under investigation include: Azacitidine (DRUG), Glutaminase Inhibitor CB-839 (DRUG).

Who is sponsoring clinical trial NCT03047993?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.