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NCT03038230 · ClinicalTrials.gov registry record · Phase 1
MCLA-117 in Acute Myelogenous Leukemia
A Phase 1 study, sponsored by Merus B.V..
- Terminated
- Registry status
- Phase 1
- Development phase
- 80
- Enrollment target
NCT03038230: Clinical Trial Phase 1 study, sponsored by Merus B.V..
NCT03038230 is a Phase 1 study that was terminated before completion, run by Merus B.V.. The registered enrollment target is 80 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03038230, a Phase 1 study, was terminated before completion, sponsored by Merus B.V..
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 80 participants
- Enrollment target
Study Summary
This is a First-in-Human, single arm, open-label, multi-national study designed to determine the safety, tolerability and preliminary efficacy of MCLA 117.
Primary Outcome
Evaluation of number of participants with treatment related toxicity observed during a dose escalation step for 1 Cycle
Interventions
- DRUG MCLA-117 bispecific antibody
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2016-04 |
| Est. Completion | 2021-05-11 |
| Phase | Phase 1 |
Why NCT03038230 stopped before completion
NCT03038230 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% higher).
The record links to 0 conditions, and to 1 intervention - of which MCLA-117 bispecific antibody is the first listed.
NCT03038230 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03038230 about?
NCT03038230 is a clinical study titled "MCLA-117 in Acute Myelogenous Leukemia". This is a First-in-Human, single arm, open-label, multi-national study designed to determine the safety, tolerability and preliminary efficacy of MCLA 117.
What is the current status of trial NCT03038230?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2016-04. Estimated completion is 2021-05-11.
What interventions are being tested in trial NCT03038230?
The interventions under investigation include: MCLA-117 bispecific antibody (DRUG).
Who is sponsoring clinical trial NCT03038230?
This trial is sponsored by Merus B.V., which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03038230's enrollment target sits among peer trials
80 672nd of 2000 higher than 1,305 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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