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NCT02997189 · ClinicalTrials.gov registry record · Phase 2
Study of OTO-104 in Subjects at Risk From Cisplatin-Induced Hearing Loss
A Phase 2 study, sponsored by Otonomy.
- Terminated
- Registry status
- Phase 2
- Development phase
- 12
- Enrollment target
NCT02997189: Clinical Trial Phase 2 study, sponsored by Otonomy.
NCT02997189 is a Phase 2 study that was terminated before completion, run by Otonomy. The registered enrollment target is 12 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02997189, a Phase 2 study, was terminated before completion, sponsored by Otonomy.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 12 participants
- Enrollment target
Study Summary
This is a multicenter, Phase 2 study to assess the feasibility, safety and efficacy of OTO-104 given by intratympanic administration in subjects at risk for ototoxicity from cisplatin chemotherapy regimens in the treatment of cancer.
Primary Outcome
Feasibility to assess incorporating OTO-104 with a cisplatin-based therapy regimen
Interventions
- DRUG OTO-104
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2016-11-15 |
| Est. Completion | 2017-09-26 |
| Phase | Phase 2 |
Why NCT02997189 stopped before completion
NCT02997189 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower).
The record links to 0 conditions, and to 1 intervention - of which OTO-104 is the first listed.
NCT02997189 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02997189 about?
NCT02997189 is a clinical study titled "Study of OTO-104 in Subjects at Risk From Cisplatin-Induced Hearing Loss". This is a multicenter, Phase 2 study to assess the feasibility, safety and efficacy of OTO-104 given by intratympanic administration in subjects at risk for ototoxicity from cisplatin chemotherapy regimens in the treatment of cancer.
What is the current status of trial NCT02997189?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2016-11-15. Estimated completion is 2017-09-26.
What interventions are being tested in trial NCT02997189?
The interventions under investigation include: OTO-104 (DRUG).
Who is sponsoring clinical trial NCT02997189?
This trial is sponsored by Otonomy, which has 20 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02997189's enrollment target sits among peer trials
12 1948th of 2000 higher than 34 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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