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NCT02987621 · ClinicalTrials.gov registry record · NA
Can Transcranial Direct Current Stimulation Improve Ambulation and Fatigue Resistance in People With MS?
A NA study, sponsored by Colorado State University.
- Completed
- Registry status
- NA
- Development phase
- 14
- Enrollment target
NCT02987621: Completed NA study, sponsored by Colorado State University.
NCT02987621 is a NA study that has completed, run by Colorado State University. The registered enrollment target is 14 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02987621, a NA study, has completed, sponsored by Colorado State University.
- COMPLETED
- Registry status
- NA
- Development phase
- 14 participants
- Enrollment target
Study Summary
In this project the investigators will be using non-invasive brain stimulation on people with multiple sclerosis (PwMS) to improve leg muscle function. Two groups of participants will be recruited. One group will perform strength testing with and without the brain stimulation. The second group of participants will perform a fatigue task, pulling against a wire at a low level of force, with and without the brain stimulation. This type of brain stimulation has been shown to transiently improve strength and fatigue measures in other populations, e.g. aged, Parkinson's, and improve cognitive abilities in people with multiple sclerosis. It is the investigator's hope that the increases in performance seen in other patient groups will also occur in people with multiple sclerosis. Future investigations will look to apply the non-invasive brain stimulation technique during physical rehabilitation to improve short and long term outcomes related to physical function.
Primary Outcome
Knee extensor strength will be tested with tDCS (less than 10V) and sham stimulation (0V). Participants performed maximal voluntary contractions (MVCs) with the knee extensors to objectively determine the weaker leg as more-affected, which was afterwards confirmed by the subject's self-report and used for the subsequent endurance task. This task consisted of a sustained isometric contraction at 15% MVC until volitional task termination and was immediately followed by a post MVC. During tDCS, st
Interventions
- DEVICE tDCS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2016-11 |
| Est. Completion | 2018-06 |
| Phase | NA |
What the finished NCT02987621 record still lists
NCT02987621 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which tDCS is the first listed.
NCT02987621 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02987621 about?
NCT02987621 is a clinical study titled "Can Transcranial Direct Current Stimulation Improve Ambulation and Fatigue Resistance in People With MS?". In this project the investigators will be using non-invasive brain stimulation on people with multiple sclerosis (PwMS) to improve leg muscle function. Two groups of participants will be recruited. One group will perform strength testing with and without the brain stimulation. The second group of pa...
What is the current status of trial NCT02987621?
This trial is currently completed. It is a NA study. The enrollment target is 14 participants. The study started on 2016-11. Estimated completion is 2018-06.
What interventions are being tested in trial NCT02987621?
The interventions under investigation include: tDCS (DEVICE).
Who is sponsoring clinical trial NCT02987621?
This trial is sponsored by Colorado State University, which has 94 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02987621's enrollment target sits among peer trials
14 1909th of 2000 higher than 90 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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