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NCT02986178 · ClinicalTrials.gov registry record · Phase 2
Lerapolturev in Recurrent Malignant Glioma
A Phase 2 study, sponsored by Istari Oncology.
- Completed
- Registry status
- Phase 2
- Development phase
- 121
- Enrollment target
NCT02986178: Completed Phase 2 study, sponsored by Istari Oncology.
NCT02986178 is a Phase 2 study that has completed, run by Istari Oncology. The registered enrollment target is 121 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02986178, a Phase 2 study, has completed, sponsored by Istari Oncology.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 121 participants
- Enrollment target
Study Summary
This is a phase 2 study of lerapolturev, an oncolytic polio/rhinovirus recombinant, in adult patients with recurrent World Health Organization (WHO) grade IV malignant glioma.
Primary Outcome
Assess objective anti-tumor response based on iRANO criteria.
Interventions
- DRUG Lomustine
- BIOLOGICAL lerapolturev
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 121 participants |
| Start Date | 2017-06-01 |
| Est. Completion | 2023-02-03 |
| Phase | Phase 2 |
What the finished NCT02986178 record still lists
NCT02986178 is an interventional study that assigns participants to a tested intervention. The registered 121 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which Lomustine is the first listed.
NCT02986178 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02986178 about?
NCT02986178 is a clinical study titled "Lerapolturev in Recurrent Malignant Glioma". This is a phase 2 study of lerapolturev, an oncolytic polio/rhinovirus recombinant, in adult patients with recurrent World Health Organization (WHO) grade IV malignant glioma.
What is the current status of trial NCT02986178?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 121 participants. The study started on 2017-06-01. Estimated completion is 2023-02-03.
What interventions are being tested in trial NCT02986178?
The interventions under investigation include: Lomustine (DRUG), lerapolturev (BIOLOGICAL).
Who is sponsoring clinical trial NCT02986178?
This trial is sponsored by Istari Oncology, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02986178's enrollment target sits among peer trials
121 567th of 2000 higher than 1,432 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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