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NCT02978144 · ClinicalTrials.gov registry record · Phase 2
Lung Imaging of Apoptosis in Chronic Obstructive Pulmonary Disease (COPD)
A Phase 2 study, sponsored by Columbia University.
- Terminated
- Registry status
- Phase 2
- Development phase
- 34
- Enrollment target
NCT02978144: Clinical Trial Phase 2 study, sponsored by Columbia University.
NCT02978144 is a Phase 2 study that was terminated before completion, run by Columbia University. The registered enrollment target is 34 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (74% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02978144, a Phase 2 study, was terminated before completion, sponsored by Columbia University.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 34 participants
- Enrollment target
Study Summary
This is a prospective interventional study examining the use of Annexin - a radioactive tracer, in assessing lung damage in healthy volunteers, healthy volunteers actively smoking, and patients with moderate and severe chronic obstructive pulmonary disease (COPD). All study participants will undergo a CT scan, pulmonary testing, and blood test. The study procedures are done in one day. The aim of this study is to determine if Annexin can be used as a marker to detect lung injury early on and aid in the future diagnosis of COPD.
Primary Outcome
Mean ± standard deviation (SD) for values for uptake of AxV-128/Tc for individual lobes and for lungs will be determined for each COPD group and compared using unpaired t-test for values with Gaussian distribution and Mann Whitney (Wilcoxon rank) test for continuous variables without normal distribution.
Interventions
- DRUG AxV-128/Tc
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2017-06-15 |
| Est. Completion | 2019-10-08 |
| Phase | Phase 2 |
Why NCT02978144 stopped before completion
NCT02978144 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (74% lower).
The record links to 0 conditions, and to 1 intervention - of which AxV-128/Tc is the first listed.
NCT02978144 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02978144 about?
NCT02978144 is a clinical study titled "Lung Imaging of Apoptosis in Chronic Obstructive Pulmonary Disease (COPD)". This is a prospective interventional study examining the use of Annexin - a radioactive tracer, in assessing lung damage in healthy volunteers, healthy volunteers actively smoking, and patients with moderate and severe chronic obstructive pulmonary disease (COPD). All study participants will undergo...
What is the current status of trial NCT02978144?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 34 participants. The study started on 2017-06-15. Estimated completion is 2019-10-08.
What interventions are being tested in trial NCT02978144?
The interventions under investigation include: AxV-128/Tc (DRUG).
Who is sponsoring clinical trial NCT02978144?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02978144's enrollment target sits among peer trials
34 1539th of 2000 higher than 448 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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