Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02960646 · ClinicalTrials.gov registry record · Phase 1

Engineered Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

A Phase 1 study, sponsored by M.D. Anderson Cancer Center.

Completed
Registry status
Phase 1
Development phase
11
Enrollment target

NCT02960646: Completed Phase 1 study, sponsored by M.D. Anderson Cancer Center.

NCT02960646 is a Phase 1 study that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 11 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist → Add completion date to calendar (.ics) →

The verdict

NCT02960646, a Phase 1 study, has completed, sponsored by M.D. Anderson Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
11 participants
Enrollment target

Study Summary

This pilot phase I trial studies the side effects of engineered donor stem cell transplant in treating patients with hematologic malignancies. Sometimes the transplanted cells from a donor can make an immune response against the body's normal cells (called graft-versus-host disease). Using T cells specially selected from donor blood in the laboratory for transplant may stop this from happening.

Interventions

  • DRUG Cyclophosphamide
  • DRUG Melphalan
  • OTHER Laboratory Biomarker Analysis
  • BIOLOGICAL Filgrastim
  • DRUG Fludarabine Phosphate

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2017-01-18
Est. Completion 2023-02-13
Phase Phase 1
M.D. Anderson Cancer Center

2,692 total trials

What the finished NCT02960646 record still lists

NCT02960646 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (82% lower).

The record links to 0 conditions, and to 5 interventions - of which Cyclophosphamide is the first listed.

NCT02960646 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02960646 about?

NCT02960646 is a clinical study titled "Engineered Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies". This pilot phase I trial studies the side effects of engineered donor stem cell transplant in treating patients with hematologic malignancies. Sometimes the transplanted cells from a donor can make an immune response against the body's normal cells (called graft-versus-host disease). Using T cells s...

What is the current status of trial NCT02960646?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 11 participants. The study started on 2017-01-18. Estimated completion is 2023-02-13.

What interventions are being tested in trial NCT02960646?

The interventions under investigation include: Cyclophosphamide (DRUG), Melphalan (DRUG), Laboratory Biomarker Analysis (OTHER), Filgrastim (BIOLOGICAL), Fludarabine Phosphate (DRUG).

Who is sponsoring clinical trial NCT02960646?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02960646's enrollment target sits among peer trials

11 1911th of 2000 higher than 88 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03114462 · 11 participants · Phase 1

    Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Laryngeal Cancer

  • NCT06039709 · 11 participants · Phase 1

    Sonodynamic Therapy in Patients With Recurrent GBM

  • NCT06425380 · 11 participants · NA

    Pilot Open-Label Trial of Resistant Potato Starch in Patients With Cirrhosis and Overt Hepatic Encephalopathy

  • NCT06472661 · 11 participants · Early Phase 1

    FUSA With Intratumoral PolyICLC in Regionally Advanced Resectable Melanoma

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT02960646, the US trial registry maintained by the National Library of Medicine. NCT02960646 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.