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NCT02950233 · ClinicalTrials.gov registry record · Phase 3
Preventing pAIn With NMDA Antagonists - Steroids in Thoracoscopic lObectomy Procedures (PAIN-STOP) Pilot Trial
A Phase 3 study, sponsored by Population Health Research Institute.
- Terminated
- Registry status
- Phase 3
- Development phase
- 27
- Enrollment target
NCT02950233: Clinical Trial Phase 3 study, sponsored by Population Health Research Institute.
NCT02950233 is a Phase 3 study that was terminated before completion, run by Population Health Research Institute. The registered enrollment target is 27 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02950233, a Phase 3 study, was terminated before completion, sponsored by Population Health Research Institute.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 27 participants
- Enrollment target
Study Summary
The objective of the PAIN-STOP trial is to assess the feasibility of a larger randomized controlled trial (RCT) evaluating NMDA antagonists and IV steroids, as compared to placebo, in decreasing the chances of clinically significant persistent post-surgical pain (PPSP) after video assisted thoracoscopic surgeries (VATS). This is a multi-centre randomized, controlled clinical trial with a 2 x 2 factorial design. The pilot phase of the trial will recruit 48 patients and follow them for 3 months. Patients will be randomized to one of four groups: 1) NMDA active + Steroid placebo; 2) Steroid active + NMDA placebo; 3) NMDA active + Steroid active; 4) NMDA placebo + Steroid placebo.
Primary Outcome
Ability to recruit 90% of eligible patients.
Interventions
- DRUG NMDA active
- DRUG Steroid active
- DRUG NMDA placebo
- DRUG Steroid placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2017-05-04 |
| Est. Completion | 2019-03-31 |
| Phase | Phase 3 |
Why NCT02950233 stopped before completion
NCT02950233 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 4 interventions - of which NMDA active is the first listed.
NCT02950233 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02950233 about?
NCT02950233 is a clinical study titled "Preventing pAIn With NMDA Antagonists - Steroids in Thoracoscopic lObectomy Procedures (PAIN-STOP) Pilot Trial". The objective of the PAIN-STOP trial is to assess the feasibility of a larger randomized controlled trial (RCT) evaluating NMDA antagonists and IV steroids, as compared to placebo, in decreasing the chances of clinically significant persistent post-surgical pain (PPSP) after video assisted thoracosc...
What is the current status of trial NCT02950233?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 27 participants. The study started on 2017-05-04. Estimated completion is 2019-03-31.
What interventions are being tested in trial NCT02950233?
The interventions under investigation include: NMDA active (DRUG), Steroid active (DRUG), NMDA placebo (DRUG), Steroid placebo (DRUG).
Who is sponsoring clinical trial NCT02950233?
This trial is sponsored by Population Health Research Institute, which has 21 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02950233's enrollment target sits among peer trials
27 1936th of 2000 higher than 64 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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