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NCT02933736 · ClinicalTrials.gov registry record · Early Phase 1

Ribociclib (LEE011) in Preoperative Glioma and Meningioma Patients

A Early Phase 1 study of Glioblastoma Multiforme and Meningioma, sponsored by Nader Sanai.

Active
Registry status
Early Phase 1
Development phase
48
Enrollment target
1
Study location

NCT02933736 is a Early Phase 1 study of Glioblastoma Multiforme and Meningioma that is active but no longer recruiting, run by Nader Sanai. The registered enrollment target is 48 participants, below the 96-participant average among 88 other Glioblastoma Multiforme trials with a reported enrollment target (50% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02933736, a Early Phase 1 study of Glioblastoma Multiforme and Meningioma, is active but no longer recruiting, sponsored by Nader Sanai.

ACTIVE NOT RECRUITING
Registry status
Early Phase 1
Development phase
48 participants
Enrollment target
1
Study location

Study Summary

In the proposed trial, patients will be administered ribociclib prior to surgical resection of their tumor. Patients will be enrolled in time-intervals sequentially (non-randomized). All patients will be orally-administered 5 doses of LEE011 (900 mg/d) with the final dose occurring at one of 3 intervals before brain tumor resection.

Interventions

  • DRUG Ribociclib

Study Locations (1)

Arizona

  • Barrow Brain and Spine - Phoenix

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2016-10-17
Est. Completion 2027-03
Phase Early Phase 1

Sponsor

Nader Sanai

13 total trials

What the Registry Record Tells You About NCT02933736

The ClinicalTrials.gov registry entry for NCT02933736 describes a study currently listed as active not recruiting, categorized as Early Phase 1. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 96-participant average among 88 other Glioblastoma Multiforme trials with a reported enrollment target (50% lower). The listed sponsor is Nader Sanai, which has 13 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Glioblastoma Multiforme appearing as the primary indexed condition, and to 1 intervention - of which Ribociclib is the first listed.

NCT02933736 reports 1 study location spanning 1 distinct geographic area - top geographies include Arizona.

Frequently Asked Questions

What is clinical trial NCT02933736 about?

NCT02933736 is a clinical study titled "Ribociclib (LEE011) in Preoperative Glioma and Meningioma Patients". In the proposed trial, patients will be administered ribociclib prior to surgical resection of their tumor. Patients will be enrolled in time-intervals sequentially (non-randomized). All patients will be orally-administered 5 doses of LEE011 (900 mg/d) with the final dose occurring at one of 3 inter...

What is the current status of trial NCT02933736?

This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 48 participants. The study started on 2016-10-17. Estimated completion is 2027-03.

What conditions does trial NCT02933736 study?

This clinical trial studies the following conditions: Glioblastoma Multiforme, Meningioma.

What interventions are being tested in trial NCT02933736?

The interventions under investigation include: Ribociclib (DRUG).

Who is sponsoring clinical trial NCT02933736?

This trial is sponsored by Nader Sanai, which has 13 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02933736 being conducted?

This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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