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NCT02925650 · ClinicalTrials.gov registry record · Phase 1
Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease
A Phase 1 study, sponsored by Annovis Bio.
- Completed
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
NCT02925650: Completed Phase 1 study, sponsored by Annovis Bio.
NCT02925650 is a Phase 1 study that has completed, run by Annovis Bio. The registered enrollment target is 18 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02925650, a Phase 1 study, has completed, sponsored by Annovis Bio.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
Study Summary
This study evaluates the safety and pharmacological effects of 3 different doses of Posiphen® when compared to a placebo, in adult male and female patients with early Alzheimer's disease (AD).
Primary Outcome
Number of adverse events or study discontinuations, broken down by dose arm (i.e. Low vs. Medium vs. High vs. Placebo), and further broken down by relatedness to Posiphen (Definitely Related, Probably Related, Possibly Related, Unlikely Related, Unrelated)
Interventions
- DRUG Placebo
- DRUG Posiphen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2017-03-02 |
| Est. Completion | 2021-12-31 |
| Phase | Phase 1 |
What the finished NCT02925650 record still lists
NCT02925650 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02925650 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02925650 about?
NCT02925650 is a clinical study titled "Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease". This study evaluates the safety and pharmacological effects of 3 different doses of Posiphen® when compared to a placebo, in adult male and female patients with early Alzheimer's disease (AD).
What is the current status of trial NCT02925650?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2017-03-02. Estimated completion is 2021-12-31.
What interventions are being tested in trial NCT02925650?
The interventions under investigation include: Placebo (DRUG), Posiphen (DRUG).
Who is sponsoring clinical trial NCT02925650?
This trial is sponsored by Annovis Bio, which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02925650's enrollment target sits among peer trials
18 1720th of 2000 higher than 216 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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