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NCT02923466 · ClinicalTrials.gov registry record · Phase 1
Ph1 Administration of VSV-IFNβ-NIS Monotherapy and in Combination With Avelumab in Pts With Refractory Solid Tumors
A Phase 1 study, sponsored by Vyriad.
- Completed
- Registry status
- Phase 1
- Development phase
- 76
- Enrollment target
NCT02923466: Completed Phase 1 study, sponsored by Vyriad.
NCT02923466 is a Phase 1 study that has completed, run by Vyriad. The registered enrollment target is 76 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02923466, a Phase 1 study, has completed, sponsored by Vyriad.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 76 participants
- Enrollment target
Study Summary
This is a three-part open label phase 1 study designed to determine the safety profile, MTD, PK and tumor and biomarker response after IT or IV administration of a single dose of VSV-IFNβ-NIS, or combined IT followed by IV VSV-IFNβ-NIS, with or without IV avelumab every two weeks, in patients with refractory advanced/metastatic solid tumors.
Interventions
- BIOLOGICAL VSV-IFNβ-NIS
- BIOLOGICAL VSV-IFNβ-NIS and avelumab
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 76 participants |
| Start Date | 2017-04-17 |
| Est. Completion | 2022-04-22 |
| Phase | Phase 1 |
What the finished NCT02923466 record still lists
NCT02923466 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 76 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% higher).
The record links to 0 conditions, and to 2 interventions - of which VSV-IFNβ-NIS is the first listed.
NCT02923466 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02923466 about?
NCT02923466 is a clinical study titled "Ph1 Administration of VSV-IFNβ-NIS Monotherapy and in Combination With Avelumab in Pts With Refractory Solid Tumors". This is a three-part open label phase 1 study designed to determine the safety profile, MTD, PK and tumor and biomarker response after IT or IV administration of a single dose of VSV-IFNβ-NIS, or combined IT followed by IV VSV-IFNβ-NIS, with or without IV avelumab every two weeks, in patients with r...
What is the current status of trial NCT02923466?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 76 participants. The study started on 2017-04-17. Estimated completion is 2022-04-22.
What interventions are being tested in trial NCT02923466?
The interventions under investigation include: VSV-IFNβ-NIS (BIOLOGICAL), VSV-IFNβ-NIS and avelumab (BIOLOGICAL).
Who is sponsoring clinical trial NCT02923466?
This trial is sponsored by Vyriad, which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02923466's enrollment target sits among peer trials
76 705th of 2000 higher than 1,290 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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