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NCT02896192 · ClinicalTrials.gov registry record · Phase 3

Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity

A Phase 3 study, sponsored by Rhythm Pharmaceuticals.

Completed
Registry status
Phase 3
Development phase
15
Enrollment target

NCT02896192 is a Phase 3 study that has completed, run by Rhythm Pharmaceuticals. The registered enrollment target is 15 participants.

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The verdict

NCT02896192, a Phase 3 study, has completed, sponsored by Rhythm Pharmaceuticals.

COMPLETED
Registry status
Phase 3
Development phase
15 participants
Enrollment target

Study Summary

To demonstrate statistically significant and clinically meaningful effects of setmelanotide on percent body weight change in participants with pro-opiomelanocortin (POMC) deficiency or proprotein convertase subtilisin/kexin type 1 (PCSK1) deficiency obesity due to rare biallelic or loss-of function mutations at the end of 1 year of treatment.

Interventions

  • DRUG Placebo
  • DRUG Setmelanotide

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2017-02-14
Est. Completion 2020-05-25
Phase Phase 3

Sponsor

Rhythm Pharmaceuticals

23 total trials

What the Registry Record Tells You About NCT02896192

The ClinicalTrials.gov registry entry for NCT02896192 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Rhythm Pharmaceuticals, which has 23 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02896192 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02896192 about?

NCT02896192 is a clinical study titled "Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity". To demonstrate statistically significant and clinically meaningful effects of setmelanotide on percent body weight change in participants with pro-opiomelanocortin (POMC) deficiency or proprotein convertase subtilisin/kexin type 1 (PCSK1) deficiency obesity due to rare biallelic or loss-of function ...

What is the current status of trial NCT02896192?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 15 participants. The study started on 2017-02-14. Estimated completion is 2020-05-25.

What interventions are being tested in trial NCT02896192?

The interventions under investigation include: Placebo (DRUG), Setmelanotide (DRUG).

Who is sponsoring clinical trial NCT02896192?

This trial is sponsored by Rhythm Pharmaceuticals, which has 23 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.