Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02893982 · ClinicalTrials.gov registry record · Phase 1
High Dose Rate Brachyablation of Primary Liver Lesions
A Phase 1 study, sponsored by University of Texas Southwestern Medical Center.
- Terminated
- Registry status
- Phase 1
- Development phase
- 1
- Enrollment target
NCT02893982: Clinical Trial Phase 1 study, sponsored by University of Texas Southwestern Medical Center.
NCT02893982 is a Phase 1 study that was terminated before completion, run by University of Texas Southwestern Medical Center. The registered enrollment target is 1 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02893982, a Phase 1 study, was terminated before completion, sponsored by University of Texas Southwestern Medical Center.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 1 participants
- Enrollment target
Study Summary
The objectives of this study are to demonstrate feasibility of an optimized, image-guided pre-planned workflow to deliver at least 25 Gy to the periphery of the target lesion while maintaining established dose constraints to normal tissues, and to determine the maximum tolerated dose (MTD) while evaluating treatment delivery, safety, and efficacy utilizing a pre-planned and optimized image-guided workflow for percutaneous HDR brachytherapy of liver lesions.
Primary Outcome
Verify feasibility of HDR brachytherapy treatment and workflow for liver lesions using catheters placed under image-guided navigational techniques, to provide dosimetric coverage of liver lesions such that: 1. Minimum CTV peripheral dose ≥ 25 Gy (D100 ≥ 25 Gy) 2. 67% or 700 cc Liver \< 5 Gy 3. Esophagus, stomach, bowel, or duodenum \< 15 Gy to 1cc, \< 12 Gy to 5cc, \< 9 Gy to 10cc, and 85 Gy in BED(2Gy) equivalent including current and prior treatment to 1cc 4. Spinal cord/cauda equina \< 8 Gy
Interventions
- RADIATION brachytherapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2017-11-09 |
| Est. Completion | 2020-03-16 |
| Phase | Phase 1 |
Why NCT02893982 stopped before completion
NCT02893982 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which brachytherapy is the first listed.
NCT02893982 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02893982 about?
NCT02893982 is a clinical study titled "High Dose Rate Brachyablation of Primary Liver Lesions". The objectives of this study are to demonstrate feasibility of an optimized, image-guided pre-planned workflow to deliver at least 25 Gy to the periphery of the target lesion while maintaining established dose constraints to normal tissues, and to determine the maximum tolerated dose (MTD) while eva...
What is the current status of trial NCT02893982?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 1 participants. The study started on 2017-11-09. Estimated completion is 2020-03-16.
What interventions are being tested in trial NCT02893982?
The interventions under investigation include: brachytherapy (RADIATION).
Who is sponsoring clinical trial NCT02893982?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02893982's enrollment target sits among peer trials
1 2001st of 2000 the lowest of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI