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NCT02877849 · ClinicalTrials.gov registry record
Brain Functional Connectivity in Alcohol Use Disorder
A clinical trial, sponsored by University of Minnesota.
- Completed
- Registry status
- 82
- Enrollment target
NCT02877849 is a clinical trial that has completed, run by University of Minnesota. The registered enrollment target is 82 participants.
The verdict
NCT02877849 has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- 82 participants
- Enrollment target
Study Summary
Due to the relapsing nature of alcoholism, excessive alcohol consumption represents a significant cost to US society ($249 billion in 20101). About 64% of those entering treatment will relapse within one year. New interventions targeting the underlying brain biomarkers of relapse vulnerability hold significant promise in reducing this critical public health problem. Using resting functional magnetic resonance imaging (fMRI) we have identified brain biomarkers that support long-term abstinence and brain biomarkers that predict relapse. Our data point to specific brain biomarkers that index higher relapse vulnerability at 11 weeks of abstinence. Many individuals, however, have already relapsed by this time. It is unknown whether these biomarkers can be identified earlier during the recovery period. We need to investigate whether this biomarker of relapse vulnerability can be identified during earlier stages of abstinence. Earlier identification of this biomarker will give valuable information for timely targeted interventions (e.g. closer monitoring, longer stay in treatment program, neuromodulation), increasing the chances of maintaining abstinence. The overall objective of this study is to identify biomarkers of relapse during early abstinence (2-3 weeks of abstinence). A secondary objective is to evaluate whether non-imaging measures such as craving6 and executive function7 add value to prediction models. Findings from this proposal will provide insight into the neurobiology of relapse vulnerability that will inform new treatment strategies needed to improve treatment outcome.
Interventions
- DEVICE MRI: Brain Imaging data collection
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 82 participants |
| Start Date | 2017-02-09 |
| Est. Completion | 2019-10-31 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02877849
The ClinicalTrials.gov registry entry for NCT02877849 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 82 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Minnesota, which has 966 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which MRI: Brain Imaging data collection is the first listed.
NCT02877849 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02877849 about?
NCT02877849 is a clinical study titled "Brain Functional Connectivity in Alcohol Use Disorder". Due to the relapsing nature of alcoholism, excessive alcohol consumption represents a significant cost to US society ($249 billion in 20101). About 64% of those entering treatment will relapse within one year. New interventions targeting the underlying brain biomarkers of relapse vulnerability hold ...
What is the current status of trial NCT02877849?
This trial is currently completed. The enrollment target is 82 participants. The study started on 2017-02-09. Estimated completion is 2019-10-31.
What interventions are being tested in trial NCT02877849?
The interventions under investigation include: MRI: Brain Imaging data collection (DEVICE).
Who is sponsoring clinical trial NCT02877849?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
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