Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02875301 · ClinicalTrials.gov registry record · Phase 3
Investigating Gains in Neurocognition in an Intervention Trial of Exercise
A Phase 3 study, sponsored by University of Pittsburgh.
- Completed
- Registry status
- Phase 3
- Development phase
- 648
- Enrollment target
NCT02875301: Completed Phase 3 study, sponsored by University of Pittsburgh.
NCT02875301 is a Phase 3 study that has completed, run by University of Pittsburgh. The registered enrollment target is 648 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (16% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02875301, a Phase 3 study, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 648 participants
- Enrollment target
Study Summary
This randomized control trial will examine whether a 12 month monitored exercise intervention improves brain health in cognitively normal older adults. This trial will also address several important unanswered questions: (1) Are the recommended public health guidelines of 150 minutes/week of exercise sufficient for improving cognitive performance? (2) Does exercise influence brain structure and/or function? (3) Is there a dose-response effect of exercise on the above variables such that greater amounts of exercise brings about greater benefits in cognitive and brain health? (4) What are the mechanisms by which exercise influences brain health? and (5) What factors attenuate or magnify the effects of exercise on brain and cognitive health and contribute to the individual variability in intervention outcomes?
Primary Outcome
Investigators are assessing change in cognitive function from baseline to 12 months. A comprehensive neuropsychological battery will be used that assesses 5 domains of cognitive function (Working Memory, Processing Speed, Episodic Memory, Attentional Control, and Visuospatial Function). We will perform a confirmatory factor analysis on the cognitive data and determine whether the exercise intervention influences performance as measured by these factors. There is no min and max values. These are
Interventions
- BEHAVIORAL 150 Minutes Week
- BEHAVIORAL 225 Minutes Week
- BEHAVIORAL Stretch and Tone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 648 participants |
| Start Date | 2017-09-06 |
| Est. Completion | 2023-04-11 |
| Phase | Phase 3 |
What the finished NCT02875301 record still lists
NCT02875301 is an interventional study that assigns participants to a tested intervention. The registered 648 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (16% lower).
The record links to 0 conditions, and to 3 interventions - of which 150 Minutes Week is the first listed.
NCT02875301 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02875301 about?
NCT02875301 is a clinical study titled "Investigating Gains in Neurocognition in an Intervention Trial of Exercise". This randomized control trial will examine whether a 12 month monitored exercise intervention improves brain health in cognitively normal older adults. This trial will also address several important unanswered questions: (1) Are the recommended public health guidelines of 150 minutes/week of exercis...
What is the current status of trial NCT02875301?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 648 participants. The study started on 2017-09-06. Estimated completion is 2023-04-11.
What interventions are being tested in trial NCT02875301?
The interventions under investigation include: 150 Minutes Week (BEHAVIORAL), 225 Minutes Week (BEHAVIORAL), Stretch and Tone (BEHAVIORAL).
Who is sponsoring clinical trial NCT02875301?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02875301's enrollment target sits among peer trials
648 572nd of 2000 higher than 1,429 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT07027306 · 648 participants
The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures
- NCT07164456 · 648 participants · NA
Together Stronger: A Family-centered Lifestyle Intervention for Black Prostate Cancer Survivors and Their Caregivers
- NCT02934477 · 650 participants
Prospective Assessment of Allogeneic Hematopoietic Cell Transplantation in Patients With Myelofibrosis
- NCT04579120 · 650 participants
Neuroimaging in Healthy Aging and Senile Dementia (HASD_IND)
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI