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NCT02871687 · ClinicalTrials.gov registry record · Phase 1

Effect of Statin Use on Aldosterone Secretion

A Phase 1 study, sponsored by Brigham and Women's Hospital.

Completed
Registry status
Phase 1
Development phase
103
Enrollment target

NCT02871687 is a Phase 1 study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 103 participants.

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The verdict

NCT02871687, a Phase 1 study, has completed, sponsored by Brigham and Women's Hospital.

COMPLETED
Registry status
Phase 1
Development phase
103 participants
Enrollment target

Study Summary

The purpose of this research protocol is to determine if the same effects are observed in vivo in humans through a randomized controlled study. Data regarding a novel mechanism of the widely used statin class of medications on the mineralocorticoid pathway would likely have significant clinical implications on the future management of hypertension and other cardiovascular disease given the known pleiotropy of aldosterone action.

Interventions

  • OTHER Placebo
  • DRUG Simvastatin
  • DRUG Pravastatin

Trial Details

FieldValue
Enrollment Target 103 participants
Start Date 2016-04
Est. Completion 2021-03
Phase Phase 1

Sponsor

Brigham and Women's Hospital

937 total trials

What the Registry Record Tells You About NCT02871687

The ClinicalTrials.gov registry entry for NCT02871687 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 103 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Brigham and Women's Hospital, which has 937 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT02871687 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02871687 about?

NCT02871687 is a clinical study titled "Effect of Statin Use on Aldosterone Secretion". The purpose of this research protocol is to determine if the same effects are observed in vivo in humans through a randomized controlled study. Data regarding a novel mechanism of the widely used statin class of medications on the mineralocorticoid pathway would likely have significant clinical impl...

What is the current status of trial NCT02871687?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 103 participants. The study started on 2016-04. Estimated completion is 2021-03.

What interventions are being tested in trial NCT02871687?

The interventions under investigation include: Placebo (OTHER), Simvastatin (DRUG), Pravastatin (DRUG).

Who is sponsoring clinical trial NCT02871687?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.