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NCT02871687 · ClinicalTrials.gov registry record · Phase 1
Effect of Statin Use on Aldosterone Secretion
A Phase 1 study, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- Phase 1
- Development phase
- 103
- Enrollment target
NCT02871687: Completed Phase 1 study, sponsored by Brigham and Women's Hospital.
NCT02871687 is a Phase 1 study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 103 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02871687, a Phase 1 study, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 103 participants
- Enrollment target
Study Summary
The purpose of this research protocol is to determine if the same effects are observed in vivo in humans through a randomized controlled study. Data regarding a novel mechanism of the widely used statin class of medications on the mineralocorticoid pathway would likely have significant clinical implications on the future management of hypertension and other cardiovascular disease given the known pleiotropy of aldosterone action.
Interventions
- OTHER Placebo
- DRUG Simvastatin
- DRUG Pravastatin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 103 participants |
| Start Date | 2016-04 |
| Est. Completion | 2021-03 |
| Phase | Phase 1 |
What the finished NCT02871687 record still lists
NCT02871687 is an interventional study that assigns participants to a tested intervention. The registered 103 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% higher).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT02871687 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02871687 about?
NCT02871687 is a clinical study titled "Effect of Statin Use on Aldosterone Secretion". The purpose of this research protocol is to determine if the same effects are observed in vivo in humans through a randomized controlled study. Data regarding a novel mechanism of the widely used statin class of medications on the mineralocorticoid pathway would likely have significant clinical impl...
What is the current status of trial NCT02871687?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 103 participants. The study started on 2016-04. Estimated completion is 2021-03.
What interventions are being tested in trial NCT02871687?
The interventions under investigation include: Placebo (OTHER), Simvastatin (DRUG), Pravastatin (DRUG).
Who is sponsoring clinical trial NCT02871687?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02871687's enrollment target sits among peer trials
103 541st of 2000 higher than 1,458 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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