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NCT02864290 · ClinicalTrials.gov registry record · Phase 1

A Study to Evaluate Escalating Doses of ASP1235 (AGS62P1) Given as Monotherapy in Subjects With Acute Myeloid Leukemia (AML)

A Phase 1 study, sponsored by Astellas Pharma Global Development.

Terminated
Registry status
Phase 1
Development phase
43
Enrollment target

NCT02864290 is a Phase 1 study that was terminated before completion, run by Astellas Pharma Global Development. The registered enrollment target is 43 participants.

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The verdict

NCT02864290, a Phase 1 study, was terminated before completion, sponsored by Astellas Pharma Global Development.

TERMINATED
Registry status
Phase 1
Development phase
43 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the safety and tolerability of ASP1235 (AGS62P1) given at three dosing schedules (Schedule A, every three weeks \[Q3W\] or Schedule B, every other week of a 4 week cycle \[Q2W\] or Schedule C once a week for 3 weeks of a 4 week cycle) in subjects with acute myeloid leukemia (AML) and determine the maximum tolerated dose (MTD). In addition, this study will assess the pharmacokinetics (PK), the immunogenicity and the anti-leukemic activity of ASP1235 (AGS62P1).

Interventions

  • DRUG ASP1235

Trial Details

FieldValue
Enrollment Target 43 participants
Start Date 2016-11-10
Est. Completion 2020-09-03
Phase Phase 1

Sponsor

Astellas Pharma Global Development

168 total trials

What the Registry Record Tells You About NCT02864290

The ClinicalTrials.gov registry entry for NCT02864290 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 43 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Astellas Pharma Global Development, which has 168 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which ASP1235 is the first listed.

NCT02864290 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02864290 about?

NCT02864290 is a clinical study titled "A Study to Evaluate Escalating Doses of ASP1235 (AGS62P1) Given as Monotherapy in Subjects With Acute Myeloid Leukemia (AML)". The purpose of this study is to evaluate the safety and tolerability of ASP1235 (AGS62P1) given at three dosing schedules (Schedule A, every three weeks \[Q3W\] or Schedule B, every other week of a 4 week cycle \[Q2W\] or Schedule C once a week for 3 weeks of a 4 week cycle) in subjects with acute m...

What is the current status of trial NCT02864290?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 43 participants. The study started on 2016-11-10. Estimated completion is 2020-09-03.

What interventions are being tested in trial NCT02864290?

The interventions under investigation include: ASP1235 (DRUG).

Who is sponsoring clinical trial NCT02864290?

This trial is sponsored by Astellas Pharma Global Development, which has 168 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.