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NCT02857270 · ClinicalTrials.gov registry record · Phase 1

A Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic Cancer

A Phase 1 study, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 1
Development phase
210
Enrollment target

NCT02857270: Completed Phase 1 study, sponsored by Eli Lilly and Company.

NCT02857270 is a Phase 1 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 210 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (250% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02857270, a Phase 1 study, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 1
Development phase
210 participants
Enrollment target

Study Summary

The purpose of this study is to determine the safety of an extracellular signal regulated kinase (ERK1/2) inhibitor LY3214996 administered alone or in combination with other agents in participants with advanced cancer.

Interventions

  • DRUG Midazolam
  • DRUG Abemaciclib
  • DRUG Gemcitabine
  • DRUG Nab-paclitaxel
  • DRUG LY3214996

Trial Details

FieldValue
Enrollment Target 210 participants
Start Date 2016-09-29
Est. Completion 2022-10-24
Phase Phase 1
Eli Lilly and Company

1,341 total trials

What the finished NCT02857270 record still lists

NCT02857270 is an interventional study that assigns participants to a tested intervention. The registered 210 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (250% higher).

The record links to 0 conditions, and to 5 interventions - of which Midazolam is the first listed.

NCT02857270 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02857270 about?

NCT02857270 is a clinical study titled "A Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic Cancer". The purpose of this study is to determine the safety of an extracellular signal regulated kinase (ERK1/2) inhibitor LY3214996 administered alone or in combination with other agents in participants with advanced cancer.

What is the current status of trial NCT02857270?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 210 participants. The study started on 2016-09-29. Estimated completion is 2022-10-24.

What interventions are being tested in trial NCT02857270?

The interventions under investigation include: Midazolam (DRUG), Abemaciclib (DRUG), Gemcitabine (DRUG), Nab-paclitaxel (DRUG), LY3214996 (DRUG).

Who is sponsoring clinical trial NCT02857270?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02857270's enrollment target sits among peer trials

210 245th of 2000 higher than 1,751 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02857270, the US trial registry maintained by the National Library of Medicine. NCT02857270 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.